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Osteoarthritis year in review 2024: genetics, genomics, and epigenetics.
Osteoarthritis and CartilageOBJECTIVE The purpose of this narrative review is to highlight the advances made in the past 12 months in the field of osteoarthritis genetics, genomics and epigenetics. METHODS The Medline and Embase databases were systematically searched for original
C. Boer
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Genomics and Genetic Engineering
2011The hurricane growth of genomics and genetic engineering poses challenging ethical questions pertaining to the technological application in human life. Many secular and religious bioethicists observe that the new proposals of genetic engineering are described as “playing God.” The metaphor has evoked both optimistic and pessimistic perspectives among ...
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2016
This chapter focuses on common empirical methods for studying the genetics of adaptation: quantitative genetics, quantitative trait locus (QTL) linkage mapping, association mapping, genome scans, gene expression, and candidate genes. It addresses various aspects of adaptation, speciation, and eco-evolutionary dynamics.
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This chapter focuses on common empirical methods for studying the genetics of adaptation: quantitative genetics, quantitative trait locus (QTL) linkage mapping, association mapping, genome scans, gene expression, and candidate genes. It addresses various aspects of adaptation, speciation, and eco-evolutionary dynamics.
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Genetics and genomics of uniformity and resilience in livestock and aquaculture species: A review.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie, 2019Genetic control of residual variance offers opportunities to increase uniformity and resilience of livestock and aquaculture species. Improving uniformity and resilience of animals will improve health and welfare of animals and lead to more homogenous ...
Laiza H S Iung +3 more
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2018
Genetics has undergone several significant technological advances since the early 1960s, which have dramatically expanded the application of genetics across life sciences, most recently into the field of genomics, which is a subarea of genetics. Consequently, genetic methods are employed not only to study genetics per se, but also as an indirect means ...
Palsbøll, Per J. +2 more
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Genetics has undergone several significant technological advances since the early 1960s, which have dramatically expanded the application of genetics across life sciences, most recently into the field of genomics, which is a subarea of genetics. Consequently, genetic methods are employed not only to study genetics per se, but also as an indirect means ...
Palsbøll, Per J. +2 more
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Asthma genetics and genomics 2009
Current Opinion in Genetics & Development, 2009Asthma Genetic Association studies have been plagued by methodologic problems that are common in all studies of complex traits: small sample size, lack of replication, and lack of control of population stratification. Despite this, the field has identified 43 replicated genes from association studies. The most frequently replicated are: TNF alpha, IL4,
Scott T, Weiss +2 more
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GENETICS/GENOMICS AND DRUG EFFECTS
Acta Clinica Belgica, 2013Differences in response to medications both in terms of clinical activity and side-effects have long been recognised by physicians. Genetics has been recently considered as a potential factor to explain part of this variability. Pharmacogenetics focuses on the variants within one or more candidate genes while pharmacogenomics evaluates the entire ...
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Genetics and Genomics of Endometriosis
2019Endometriosis is an estrogen-dependent, progesterone-resistant, inflammatory disease with symptoms that include pelvic pain, infertility, and compromised quality of life in millions of women worldwide. Approximately 50% of the risk of developing endometriosis is due to genetic factors with the remaining 50% due to environmental (i.e., exposome) causes.
Giudice, Linda C. +7 more
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