Results 231 to 240 of about 6,322,056 (300)

Statement on Clinical Genetics and Freedom of Choice

, 1991

core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The evolution of hereditary cancer genetic counselling: mainstreaming, service redesign and patient experience in Lynch syndrome. [PDF]

Fam Cancer
Kohut K, Cable S, Ashokan A, Vicari S, Ditchfield H, Young J, Bux B, Lalloo F.   +7 more
europepmc   +1 more source

Assessing Genomic Competencies: Insights From the Genetics and Genomics Nursing Practice Survey (GGNPS). [PDF]

Nurs Res Pract
Salameh MI, Khalil AA.
europepmc   +1 more source

Expert consensus on the reporting and clinical follow up of individuals with incidentally discovered germline RET variants in the UK. [PDF]

Endocr Relat Cancer
Hanson H, Snape K, Dias RP, Park SM, Shaikh MG, Kurzawinski TR, Izatt L, Patel KA, Korbonits M, Casey RT.   +9 more
europepmc   +1 more source

Teaching Cell and Gene Therapy in Genetic Counseling Programs: Survey Findings and Suggested Practical Resources for Integration. [PDF]

J Genet Couns
Sebby M, McConachie L, Wetherill L, Delk P, Hopewell EL.   +4 more
europepmc   +1 more source

Artificial intelligence in clinical genetics: Current practice and attitudes among the clinical genetics workforce. [PDF]

Genet Med
Berkstresser AM, Ledgister Hanchard SE, Iacaboni D, McMilian K, Duong D, Solomon BD, Waikel RL.   +6 more
europepmc   +1 more source

Author response to Commentary on "Long-term safety and efficacy of deoxycytidine/deoxythymidine in treatment of POLG-related disorders". [PDF]

Neurotherapeutics
Myers KA, Buhas D, Waters PJ.
europepmc   +1 more source

[Genetics in clinical hematology. I. The principles of clinical genetics].

Acta haematologica Polonica, 1988
openaire   +1 more source