Results 51 to 60 of about 247,762 (263)

Prediction of expected performance for a genetic programming classifier [PDF]

Genetic Programming and Evolvable Machines, 2016
The study of problem difficulty is an open issue in Genetic Programming (GP). Thegoal of this work is to generate models that predict the expected performance of a GPbasedclassifier when it is applied to an unseen task. Classification problems aredescribed using domain-specific features, some of which are proposed in this work,and these features are ...
Yuliana Martínez, Leonardo Trujillo 0001, Pierrick Legrand, Edgar Galván López   +3 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Genetics of Brain Fiber Architecture and Intellectual Performance [PDF]

The Journal of Neuroscience, 2009
The study is the first to analyze genetic and environmental factors that affect brain fiber architecture and its genetic linkage with cognitive function. We assessed white matter integrity voxelwise using diffusion tensor imaging at high magnetic field (4 Tesla), in 92 identical and fraternal twins.
Chiang, Ming-Chang, Barysheva, Marina, Shattuck, David, Lee, Agatha, Madsen, Sarah, Avedissian, Christina, Klunder, Andrea, Toga, Arthur, McMahon, Katie, de Zubicaray, Greig, Wright, Margie, Srivastava, Anuj, Balov, Nikolay, Thompson, Paul   +13 more
openaire   +5 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Visualizing the Invisible: The Impact of Computer Simulations on Student Attitude Towards Genetics Education [PDF]

Journal of Research in Science, Mathematics and Technology Education
This study investigates senior high school students’ attitudes toward the use of computer simulations in the teaching and learning of genetics in Ghana.
Maxwell Gyamfi, Isaac Owusu, Charles Amoah Agyei, Eric Appiah-Twumasi   +3 more
doaj   +1 more source

Defining locality in genetic programming to predict performance [PDF]

IEEE Congress on Evolutionary Computation, 2010
A key indicator of problem difficulty in evolutionary computation problems is the landscape's locality, that is whether the genotype-phenotype mapping preserves neighbourhood. In genetic programming the genotype and phenotype are not distinct, but the locality of the genotype-fitness mapping is of interest. In this paper we extend the original standard
Edgar Galván López, James McDermott, Michael O'Neill 0001, Anthony Brabazon   +3 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Assessing the Genetics Content in the Next Generation Science Standards. [PDF]

PLoS ONE, 2015
Science standards have a long history in the United States and currently form the backbone of efforts to improve primary and secondary education in science, technology, engineering, and math (STEM). Although there has been much political controversy over
Katherine S Lontok, Hubert Zhang, Michael J Dougherty   +2 more
doaj   +1 more source

Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant

Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke, Julia Wang, Haley Newman, Evelyn Kurpiewski, Anne Reilly, Susan R. Rheingold, Gerald Wertheim, Moe Takeda, Daniel J. Zheng, Kaitlin Devine   +9 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source