Results 211 to 220 of about 1,175,699 (274)

UCell and pyUCell: single-cell gene signature scoring for R and Python. [PDF]

Bioinformatics
Andreatta M, Carmona SJ.
europepmc   +1 more source

Impact of a booster intervention of the 'More Time at Patients' Side' programme on patients and healthcare professionals in a Swiss hospital: protocol for a cluster randomised controlled trial. [PDF]

BMJ Open
Buclin CP, Bürgisser N, Mongin D, Le Mauguen A, Farhoumand PD, Berner A, Daverio JE, Barrios J, Reny JL, Courvoisier DS, Agoritsas T.   +10 more
europepmc   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Long-term Anatomical and Functional Outcomes Following Surgical Repair of Open Globe Injuries: A 10-Year Retrospective Study. [PDF]

Klin Monbl Augenheilkd
Bravetti GE, Blavakis E, Hufschmitt-Henry S, Thumann G.   +3 more
europepmc   +1 more source

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

Prevalence of alcohol consumption and awareness of consumption guidelines: A population-based study in Geneva, Switzerland. [PDF]

Prev Med Rep
Dumont R, Baysson H, Mechoullam S, Mettraux C, Stringhini S, Guessous I, Nehme M.   +6 more
europepmc   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Sepsis outbreak following a probable extrinsic contamination of propofol by Escherichia coli, Geneva, 2024. [PDF]

Antimicrob Resist Infect Control
Petrucci R, Allaoua A, Metsini A, Cherkaoui A, Vu DL, Lazarevic V, Perreard D, Haroutunian N, Garcin S, Grosgurin O, Vernaz N, Harbarth S, Regard S, Schrenzel J, Cassini A.   +14 more
europepmc   +1 more source

List of SL divisional reports published in 1997 [PDF]

, 1998
CERN. Geneva, CERN. Geneva
core