Results 71 to 80 of about 9,138,035 (263)
Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq
Advanced Science, EarlyView.Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su +10 more
wiley +1 more source
Gender gap in faculty promotion.
PLoS ONEWe examine the gender gap in faculty promotion at the University of Geneva. After building a new measure of research quality that has no gender bias (i.e. men and women have, on average, the same level of research quality after we control for disciplines)
Agata Czech +2 more
doaj +1 more source
Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Jixie chuandong, 2012 Based on the theory of the elastodynamics and the structure characteristic of Geneva,the finite element method is used to establish the kinetic equation of the mechanism.Therefore,by solving the equations,all kinds of dynamic parameters are determined ...
黄剑锋, 吴宏武
doaj
Advanced Science, EarlyView.An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng +17 more
wiley +1 more source
Journal of Pain Research, 2023 Christophe Mallet,1 Jules Desmeules,2 Rassa Pegahi,3 Alain Eschalier1 1Université Clermont Auvergne, INSERM, NEURO-DOL Basics & Clinical Pharmacology of Pain, Clermont-Ferrand, France; 2Faculty of Medicine and The School of Pharmaceutical Sciences ...
Mallet C +3 more
doaj
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
International Legal Responsibility for Drone Operations Violating the Principle of Distinction in Civilian Areas [PDF]
SHS Web of ConferencesInternational humanitarian law (IHL) has three main principles that guide armed conflict, one of which is the principle of distinction. This principle affirms the obligation of every party to a conflict to distinguish between combatants and civilians ...
Dwika Ariestu I Putu +6 more
doaj +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Journal of Integrative Agriculture, 2016 The aim of this study was to investigate the impact of heat stress on physiological features, together with endogenous hormones and the transcription level of related genes, to estimate the heat resistance ability and stress injury mechanism of different
Bei-bei ZHOU +5 more
doaj +1 more source