Results 171 to 180 of about 4,154,048 (298)

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

open access: yesThe FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro   +13 more
wiley   +1 more source

Diagnostic competence and health worker knowledge of female genital schistosomiasis management in a rural Ghanaian district. [PDF]

open access: yesPLoS Negl Trop Dis
Gbeze C   +7 more
europepmc   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

open access: yesHistopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Additional sectioning and AI‐assisted diagnosis reveal underdiagnosis of serous (pre)malignancies in fallopian tube specimen from BRCA1/2 carriers

open access: yesHistopathology, EarlyView.
This paper shows that deeper sections reveal additional STICs and HGSCs in risk‐reducing salpingo‐oophorectomy specimens of patients who did not have a STIC or HGSC diagnosis but did develop peritoneal HGSC 10 years after surgery. This adds to the premise that HGSC originates in the fallopian tube.
Anouk B Bouwmeester   +17 more
wiley   +1 more source

Isolated Ovarian Tuberculosis Mimicking Ovarian Malignancy in a Young Female with Primary Infertility: A Case Report. [PDF]

open access: yesInt Med Case Rep J
Sarwary MF   +7 more
europepmc   +1 more source

Distinct Rb expression pattern in HPV‐associated neuroendocrine carcinomas of the uterine cervix

open access: yesHistopathology, EarlyView.
Most uterine cervical neuroendocrine carcinoma (UCNEC) cases are HPV‐associated and are characterized by partial loss of Rb, p16 overexpression, and cyclin D1 negativity. A minority of UCNECs exhibit a distinct pattern, characterized by HPV negativity, retained Rb expression, focal p16 expression and cyclin D1 positivity.
Nobuko Yasutake   +12 more
wiley   +1 more source

Same‐night PrEP in community care: The Nightcafé model for male and transgender sex workers

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Despite high risk of HIV infection, uptake of pre‐exposure prophylaxis (PrEP) remains limited among male and transgender sex workers (MSW and TSW), and data on tailored interventions to improve access are scarce. The Nightcafé programme addresses this gap by offering low‐threshold PrEP provision in a community‐centred setting ...
Elena Heizmann   +9 more
wiley   +1 more source

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