ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
Sexual Safety Signals of Common Antidiabetic Drugs: Insights From FAERS Disproportionality Analysis
ABSTRACT Background Erectile dysfunction is a prevalent and distressing complication of diabetes mellitus that markedly affects quality of life in male patients. Although the role of diabetes in erectile dysfunction is well‐established, potential drug‐induced sexual dysfunction associated with commonly prescribed antidiabetic medications remains ...
Shan Lin +3 more
wiley +1 more source
Costs and health consequences of chlamydia management strategies among pregnant women in sub-Saharan Africa [PDF]
Objectives: Chlamydia is the most common bacterial sexually transmitted infection worldwide and a major cause of morbidity – particularly among women and neonates.
Kristiansen, Ivar Sønbø +6 more
core
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Pubertal Timing Associates With Cardiometabolic Markers During Puberty and in Young Adulthood
ABSTRACT Aim To study how pubertal timing associates with cardiometabolic measures in puberty and young adulthood. Methods Cardiovascular risk factors, anthropometry and pubertal development were regularly studied in STRIP study subjects until age 26 years.
Saga Nummela +7 more
wiley +1 more source
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee +6 more
wiley +1 more source
International Delphi consensus on feminising genital surgery in assigned‐male‐at‐birth individuals
Objective To achieve an international expert consensus among surgeons on the indications, contraindications, and perioperative management of feminising genital surgery (FGS) for assigned‐male‐at‐birth (AMAB) individuals, using a Delphi process. Methods A two‐round on‐line Delphi survey (May–July 2025) followed by a final consensus meeting (September ...
Marta Pezzoli +30 more
wiley +1 more source
Rare clinical presentations of paracoccidioidomycosis: Epidemiological, clinical, and microbiological insights from a Brazilian reference center. [PDF]
Agrizzi LC +9 more
europepmc +1 more source
Male Genital Reconstruction for Benign Disease: A Single Centre Experience
C. Kelly +7 more
openaire +2 more sources
Trichophyton mentagrophytes Genotype VII: Sexually Transmitted Infection Beyond MSM
Australasian Journal of Dermatology, EarlyView.
Gabriele Perego +5 more
wiley +1 more source

