Results 21 to 30 of about 44,902 (199)

Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

ESC Heart Failure, EarlyView.
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang, Rui Fan, Shaozhao Zhang, Junlin Zhong, Yiquan Huang, Peihan Xie, Shanshan Yin, Xiaomin Ye, Xinghao Xu, Rihua Huang, Zhenyu Xiong, Yue Guo, Menghui Liu, Yifen Lin, Suhua Li, Xiaoxian Qian, Jinlai Liu, Xiaodong Zhuang, Xinxue Liao   +18 more
wiley   +1 more source

Alternative MYB Promoter Activity Is a Potential Prognostic Biomarker in Head and Neck Adenoid Cystic Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is an aggressive therapy‐resistant head and neck cancer with a high frequency of local recurrences and distant metastases. Activation of the MYB gene, encoding an oncogenic master transcription factor, is the key genomic hallmark of ACC and a potential therapeutic target. Here, we have investigated the
Fredrik Jäwert, André Fehr, Marta Persson, Adel K. El‐Naggar, Göran Stenman, Mattias K. Andersson   +5 more
wiley   +1 more source

A rare case of perineal neuralgia treated with ultrasound‐guided nerve block combined with water separation

Ibrain, Volume 11, Issue 1, Page 106-111, Spring 2025.
A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang, Min Wang, Rui Jiang, Zhao‐Qiong Zhu, Guang‐Cai Li   +4 more
wiley   +1 more source

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

International Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk, Emma L. Kaderly Rasmussen, Charlotte Gerd Hannibal, Rasmus Hertzum‐Larsen, Louise Baandrup, Susanne K. Kjær   +5 more
wiley   +1 more source

Socioeconomic impact among and socioeconomic support services for adolescents and young adults with cancer: A European perspective

International Journal of Cancer, EarlyView.
What's New? This novel analysis of the socioeconomic impact of cancer on adolescents and young adults (AYAs) across 11 European countries highlights the severe financial challenges faced by this patient group. The study integrates patient perspectives with healthcare provider insights, revealing that 79% of AYAs experience financial difficulties and 65%
Julie M. Vancoppenolle, Silvie H. M. Janssen, Nora Franzen, Winette T. A. van der Graaf, Valesca Retel, Olga Husson, Wim van Harten   +6 more
wiley   +1 more source

A road map through the multi‐faceted world of female genital cosmetic surgical techniques

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The demand for female genital cosmetic surgery (FGCS) has significantly increased in recent years for two reasons: the advancement of surgical operations and the increased attention to women's esthetic and sexual well‐being. Three authors independently analyzed different databases up to April 1, 2024.
Giovanni Buzzaccarini, Rebecca Susanna Degliuomini, Laura De Rosa, Silvia Villa, Silvia Messina, Gabriele Siesto, Massimo Candiani, Stefano Salvatore   +7 more
wiley   +1 more source

Antimicrobial Susceptibility Profile of Eggerthella lenta Isolated From Bloodstream and Abdominal Fluid Infections

iLABMED, EarlyView.
Antimicrobial susceptibility analysis of clinical Eggerthella lenta isolates. This study reviewed 36 E. lenta isolates from the bloodstream and abdominal fluids (2018–2024). Identification methods included VITEK 2 ANC, MALDI‐TOF, and 16S rRNA sequencing. Antimicrobial susceptibility testing using agar dilution followed CLSI and EUCAST guidelines.
Yuan Gao, Longfeng Qu, Shu Zhang, Cheng Cheng, Bin Tang   +4 more
wiley   +1 more source

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

Journal of Clinical Laboratory Analysis, EarlyView.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao, Wei Zuo, Qing Xiang, Yafeng Xie, Yongjian Xiao   +4 more
wiley   +1 more source

The educational effects of telemedicine training using role‐playing for general practice/family medicine residents: A qualitative study

Journal of General and Family Medicine, EarlyView.
Abstract Background Despite the increasing demand for telemedicine, there have been few reports on telemedicine training for general practice/family medicine residents. This study aimed to qualitatively examine the educational effects of remote medical training for residents using role‐play.
Koki Nakamura, Tomoo Hidaka, Yoshihiro Toyoda, Mei Endo, Satoshi Kanke   +4 more
wiley   +1 more source

Upadacitinib for difficult‐to‐treat paediatric Crohn's disease

JPGN Reports, EarlyView.
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou, S. Sharma, M. Khalid, C. Hinchliffe   +3 more
wiley   +1 more source