Results 131 to 140 of about 18,900 (226)

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Marburg Virus Disease: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
wiley   +1 more source

Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster

Journal of Applied Toxicology, Volume 45, Issue 5, Page 841-857, May 2025.
ABSTRACT N‐Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is because of the metabolites associated with its biotransformation. The metabolism of NDMA produces formaldehyde, another alkylating agent and DBP. Both compounds are generated from
Oscar Eduardo Tabares‐Mosquera, Javier Andrés Juárez‐Díaz, Rafael Camacho‐Carranza, Patricia Ramos‐Morales   +3 more
wiley   +1 more source

β3‐Adrenoceptor Agonism to Mimic the Biological Effects of Intrauterine Hypoxia: Taking Great Strides Toward a Pharmacological Artificial Placenta

Medicinal Research Reviews, Volume 45, Issue 3, Page 842-866, May 2025.
ABSTRACT At different stages of life, from embryonic to postnatal, varying oxygen concentrations modulate cellular gene expression by enhancing or repressing hypoxia‐inducible transcription factors. During embryonic/fetal life, these genes encode proteins involved in adapting to a low‐oxygen environment, including the induction of specific enzymes ...
Luca Filippi, Francesca Innocenti, Francesca Pascarella, Rosa Teresa Scaramuzzo, Riccardo Morganti, Paola Bagnoli, Maurizio Cammalleri, Massimo Dal Monte, Maura Calvani, Alessandro Pini   +9 more
wiley   +1 more source

Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development

Molecular Reproduction and Development, Volume 92, Issue 5, May 2025.
ABSTRACT Germ cells are pivotal for the continuation of biological species. The metazoan germline develops from primordial germ cells (PGCs) that undergo multiple rounds of mitotic divisions. The PGCs are specified by either maternal inheritance of asymmetrically polarized cytoplasmic mRNAs/proteins (found in roundworms, flies, fishes, frogs, and fowl)
Indrashis Bhattacharya, Lakshmi K. Nalinan, K. V. Anusree, Ahmed Saleel, Aditi Khamamkar, Souvik Dey   +5 more
wiley   +1 more source

Cellular origins of mucinous ovarian carcinoma

The Journal of Pathology, Volume 266, Issue 1, Page 9-25, May 2025.
Abstract Mucinous ovarian carcinoma (MOC) is a rare histotype of epithelial ovarian cancer. Its origins are obscure: while many mucinous tumours in the ovary are metastases from the gastrointestinal tract, MOC can occur as an ovarian primary; however, the cell of origin is not well established.
Nicola S Meagher, Martin Köbel, Anthony N Karnezis, Aline Talhouk, Michael S Anglesio, Andrew Berchuck, Simon A Gayther, Paul PD Pharoah, Penelope M Webb, Susan J Ramus, Kylie L Gorringe   +10 more
wiley   +1 more source

Loop‐Mediated Isothermal Amplification (LAMP) for the Diagnosis of Sexually Transmitted Infections: A Review

Microbial Biotechnology, Volume 18, Issue 5, May 2025.
LAMP assay for point‐of‐care tests. ABSTRACT Sexually transmitted infections (STIs) remain a significant public health concern. Given the asymptomatic nature of many STIs, diagnostic testing is critical for determining the appropriate treatment, enabling effective tracing and reducing the risk of further transmission.
Yasaman Ahmadi, Yejiong Yu, Zhanfeng Cui, Wei E. Huang, Monique I. Andersson   +4 more
wiley   +1 more source

Genetic Association Between High-Risk HPV (HPV16 and HPV18) Infection and Tumor Development: A Mendelian Randomization Analysis. [PDF]

Health Sci Rep
Wu Y, Xia H, Du F, Zhang J, Jiang X, Tang J, Li Z.   +6 more
europepmc   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 899-941, May 2025.
HS treatment algorithm. Abstract Introduction This second part of the S2k guidelines is an update of the 2015 S1 European guidelines. Objective These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS ...
C. C. Zouboulis, F. G. Bechara, F. Benhadou, V. Bettoli, Z. Bukvić Mokos, V. Del Marmol, M. Dolenc‐Voljč, E. J. Giamarellos‐Bourboulis, Ø. Grimstad, P. Guillem, B. Horváth, R. E. Hunger, J. R. Ingram, D. Ioannidis, E. Just, L. Kemény, B. Kirby, A. I. Liakou, B. M. McGrath, A. V. Marzano, Ł. Matusiak, A. Molina‐Leyva, A. Nassif, M. Podda, E. P. Prens, F. Prignano, H. Raynal, M. Romanelli, D. M. L. Saunte, A. Szegedi, J. C. Szepietowski, T. Tzellos, S. Valiukevičienė, H. H. van der Zee, K. R. van Straalen, B. Villumsen, G. B. E. Jemec   +36 more
wiley   +1 more source

Epidemiology and treatment of Adamantiades–Behçet's disease in Germany: A healthcare claims database study

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 1017-1027, May 2025.
Epidemiology, associated comorbidities and current treatment patterns of Adamantiades–Behçet's disease in Germany. Abstract Background Adamantiades–Behçet's disease (ABD) is a rare, chronic, relapsing, multisystem vasculitis, with a reported prevalence of 0.9 out of 100,000 population in Germany in 2012.
C. C. Zouboulis, J. Borchert, J. Diesing, R. Heinrich, W. Galetzka, J.‐P. Medelnik, A. Altenburg, A. Feldhus, T. Schönfelder   +8 more
wiley   +1 more source