Results 41 to 50 of about 67,144 (157)

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

Malignant Neoplasms of Male Genital Organs (C60-C63) in the Osijek-Baranja County, Croatia

Collegium antropologicum, 2014
Cancers of male genital organs (C60-C63) and in particular, prostate cancer, represent one of the most frequent cancer groups among males in economically developed countries and growing cancer group in developing countries. The Institute of Public Health of the Osijek-Baranja County in collaborate with different county institutes provide updated ...
Milas, Josip, Samardžić, Senka, Milas, Krešimir   +2 more
openaire   +3 more sources

Diagnosis and management of reactive infectious mucocutaneous eruption

Journal of Hospital Medicine, EarlyView.
Abstract Medicine's clinical understanding of reactive infectious mucocutaneous eruption (RIME) has evolved over time. It was previously described as Mycoplasma pneumoniae‐induced rash and mucositis (MIRM), and before that as a variant of Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis. Here, we summarize the current understanding of best practices
Nicole Damari, Abbie Goodman, Catherine Bridges   +2 more
wiley   +1 more source

Relative risk of second malignant neoplasms highest among young adult cancer patients – a population-based registry study in Finland

Acta Oncologica
Background and purpose: The objective of this study was to explore the incidence of second malignant neoplasms (SMNs) among adult cancer patients in Finland diagnosed with their first primary cancer (FPC) in 1992–2021.
Hanna A.M. Koivisto, Aapeli O. Nevala, Joonas M. Miettinen, Janne M. Pitkäniemi, Nea K. Malila, Sanna M.M. Heikkinen   +5 more
doaj   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Effectiveness and Safety of Advanced Dual‐Targeted Therapy in Refractory Perianal Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Perianal Crohn's disease (CD) remains challenging to treat despite the increasing number of advanced therapies. Advanced dual‐targeted therapy has emerged as a new treatment option in CD, but no data are available for perianal CD. The aim of this study was to evaluate the effectiveness and safety of advanced dual‐targeted therapy ...
Nadia Fathallah, Mario Pagano, Mohamed Amine Haouari, Amélie Barré, Calina Atanasiu, Edouard Chambenois, Isabelle Nion‐Larmurier, Stéphane Morisset, Julien Kirchgesner, Vincent de Parades   +9 more
wiley   +1 more source

Management of Vocal Fold Leukoplakia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
wiley   +1 more source

Individualized T3‐4N+ Rectal Cancer Treatment Strategies: Exploring the Efficacy of Preoperative Synchronized Lateral Lymph Node Simultaneous Integrated Boost Radiation Therapy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Anatomical Diagram: It shows a cross‐section of the pelvic area highlighting the rectum and lateral lymph nodes, which are the focal points of the treatment strategy discussed in the paper. Flowchart: It outlines the treatment process from preoperative synchronized radiation therapy to the subsequent surgical procedures, illustrating the sequence of ...
Xinjue Shi, Siyao Zhong, Xianbin Zheng, Xianxiu Nan, Xuan Liu, Qiteng Liu, Jing Yuan, Yuyan Gao   +7 more
wiley   +1 more source

Genital gender‐affirming surgery trends in Germany: Total population data with 19,600 cases from 2006 to 2022

Andrology, EarlyView.
Abstract Purpose To delineate the current trends regarding gender‐affirming surgeries (GAS) in Germany. Methods Analysis of German hospital quality reports from 2006 to 2022 was conducted using the reimbursement.info tool. The German procedure classification (OPS) codes 5‐646.0 for masculinizing‐ and 5‐646.1 for feminizing surgery were assessed to ...
Cem Aksoy, Sascha Wellenbrock, Philipp Reimold, Philipp Karschuck, Mahmut Ozturk, Tobias Hirsch, Michael Sohn, Nicole Eisenmenger, Sabine Kliesch, Saskia Morgenstern, Aristeidis Zacharis, Johannes Huber, Luka Flegar   +12 more
wiley   +1 more source