Results 41 to 50 of about 17,798 (155)

MRI of the Scrotum and Penis: Current Applications and Clinical Relevance

Diagnostics
Background: Magnetic resonance imaging (MRI) plays an increasingly important role in the evaluation of scrotal and penile disorders, complementing ultrasonography in cases where findings are equivocal or complex.
Bartosz Regent, Karolina Nowak, Katarzyna Skrobisz, Marcin Matuszewski, Michał Studniarek   +4 more
doaj   +1 more source

Reduced Visibility of Pigment Network Under Sub‐UV Reflectance Dermatoscopy Compared to Polarised Dermatoscopy: A Novel Diagnostic Clue to Differentiate Melanomas From Nevi

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Melanoma accounts for more than 75% of skin cancer‐related mortality. Dermatoscopy is an evidence‐based technique for earlier detection, yet differentiating melanocytic lesions remains challenging. Sub‐UV reflectance dermatoscopy (sUVRD) uses purple light (405 nm) to visualise chromophore distribution in the skin.
L. Dupont, P. Pietkiewicz, J. Anriot, P. Greco, A. Petiot‐Walch, C. Coste, E. Aurambout, S. Darnis, M. Amini‐Adle, L. Thomas   +9 more
wiley   +1 more source

Evaluation of Immunosuppressive Status Among HIV‐Positive Women With Cervical Cancer at Queen Elizabeth Central Hospital, Malawi

Medicine Advances, EarlyView.
This study found that cervical cancer does not significantly affect HIV viral load or systemic immune suppression in HIV‐positive women, most of whom were virally suppressed. However, age, cancer stage, and socio‐economic status were significantly associated with immunological markers, with older women and those with advanced disease showing poorer HIV
Thokozani Maluwa, Yusuf Dinala, Luis Gadama, Isaac Thom Shawa   +3 more
wiley   +1 more source

Safety and Effectiveness of Dimethyl Fumarate in Japanese Patients With Multiple Sclerosis: 2‐Year Post‐Marketing Surveillance Data

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Dimethyl fumarate (DMF) is an orally administered disease‐modifying drug used for the treatment of multiple sclerosis (MS) in numerous countries worldwide. Aim An ongoing post‐marketing surveillance (PMS) is assessing the real‐world safety and effectiveness of DMF in Japanese patients with MS.
Hirofumi Ochi, Toshiyuki Fukazawa, Takashi Yamamura, Kazumasa Yokoyama, Takashi Ohashi, Ichiro Nakashima, Masanori Mizuno, Hikoaki Fukaura, Izumi Kawachi, Tatsusada Okuno, Ryusuke Sato, Haruki Makioka, Aya Tsuchiya, Michihiro Kanda, Yayoi Sato, Takahiko Saida   +15 more
wiley   +1 more source

An RNA interference biopesticide reduces reproduction of the honey bee parasite Varroa destructor by down‐regulating embryo development pathways

Pest Management Science, EarlyView.
Varroa destructor mites exposed to dsRNA specific in sequence to a V. destructor calmodulin gene significantly effected gene expression of adult female mites sampled 5 days after entering a honey bee brood cell to reproduce. Significantly down‐regulated genes included Calmodulin and were associated with calcium ion binding and embryo developmental ...
Zoe E Smeele, Rose A McGruddy, James W Baty, Brian Manley, Kenneth Narva, Emma De Neef, Eric RL Gordon, Upendra K Devisetty, Katie Youngs, Antoine Felden, Philip J Lester   +10 more
wiley   +1 more source

Management of Vocal Fold Leukoplakia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
wiley   +1 more source

C‐Reactive Protein Kinetics as Prognostic Biomarkers in Stage IV‐Melanoma Treated With Immune Checkpoint Inhibitors in the Japanese Population: A Single‐Center, Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Malignant melanoma is an aggressive form of skin cancer with variable outcomes in response to immunotherapy. Although immune checkpoint inhibitors have improved survival in patients with advanced melanoma, predicting which patients will benefit from treatment remains a major clinical challenge. This study aimed to evaluate the prognostic value
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source

Individualized T3‐4N+ Rectal Cancer Treatment Strategies: Exploring the Efficacy of Preoperative Synchronized Lateral Lymph Node Simultaneous Integrated Boost Radiation Therapy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Anatomical Diagram: It shows a cross‐section of the pelvic area highlighting the rectum and lateral lymph nodes, which are the focal points of the treatment strategy discussed in the paper. Flowchart: It outlines the treatment process from preoperative synchronized radiation therapy to the subsequent surgical procedures, illustrating the sequence of ...
Xinjue Shi, Siyao Zhong, Xianbin Zheng, Xianxiu Nan, Xuan Liu, Qiteng Liu, Jing Yuan, Yuyan Gao   +7 more
wiley   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

Andrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani, María Otero‐Alén, Juan Suárez‐Quintanilla, Marina Gándara‐Cortés, Tomás García‐Caballero, Rosalía Gallego, Lucía García‐Caballero   +6 more
wiley   +1 more source

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus

Andrology, EarlyView.
ABSTRACT Background Lichen sclerosus is a chronic, inflammatory, scarring disease of the skin that manifests mostly in the genital region. Objective We studied the histomorphological characteristics, grade, and pattern of inflammation in male pediatric patients with lichen sclerosus.
Valerie Flammang, Arndt Hartmann, Robert Stöhr, Katrin Weigelt, Carol Geppert, Frederik A. Stuebs, Matthias W. Beckmann, Bernd Wullich, Helge Taubert, Marios Marcou, Sven Wach   +10 more
wiley   +1 more source