Results 41 to 50 of about 172,455 (200)

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Surgical Management of Diabetic Foot Ulcers: A Tanzanian University Teaching Hospital Experience. [PDF]

, 2011
\ud \ud Diabetic foot ulcers (DFUs) pose a therapeutic challenge to surgeons, especially in developing countries where health care resources are limited and the vast majority of patients present to health facilities late with advanced foot ulcers.
Kabangila Rodrick, Gilyoma, J.M., Mbelenge, N., Gilyoma, Japhet M, Rodrick Kabangila, Dass, R.M., Phillipo L Chalya, Chalya Phillipo L, Joseph B Mabula, Mchembe Mabula D, Jaka Hyasinta, Jaka, H., Nkinda Mbelenge, Mchembe, M.D., Jaka, Hyasinta, Mabula Joseph B, Kataraihya, Johannes B, Mbelenge, Nkinda, Gilyoma Japhet M, Mabula D Mchembe, Johannes B Kataraihya, Kataraihya, J.B., Dass Ramesh M, Chalya, Phillipo L, Chalya, P.L., McHembe, Mabula D, Kabangila, Rodrick, Mabula, J.B., Hyasinta Jaka, Dass, Ramesh M, Mbelenge Nkinda, Kataraihya Johannes B, Kabangila, R., Ramesh M Dass, Japhet M Gilyoma, Mabula, Joseph B   +35 more
core   +1 more source

Photo Quiz: Globose Yeast‐Like Forms With Multiple Peripheral Buds in Urine and Cervical Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT A 26‐year‐old immunocompetent woman with a history of noninvasive, low‐grade papillary urothelial carcinoma presented with persistent upper abdominal pain. Urine cytology, performed for bladder tumor surveillance, revealed globose, yeast‐like forms (10–30 μm) with thick walls and multiple narrowly attached peripheral buds in a “ship wheel ...
Adil Menon, Rachel Koch, Caroline Abramovich   +2 more
wiley   +1 more source

Women and genital cosmetic surgery [PDF]

, 2013
This Issues Paper critically explores female genital cosmetic surgery in the Victorian context: to better understand what it is, who is undertaking it, and their reasons for doing so.
Jessica Malone
core  

The skin in Behçet's disease: Mucocutaneous findings and differential diagnosis

JEADV Clinical Practice, 2022
Behçet's disease (BD) is a chronic multisystemic inflammatory disease with vasculitis and skin findings. Attacks and remissions characterize the course of the disease. In general, the disease activity decreases with advanced age.
Seçil Vural, Ayşe Boyvat
doaj   +1 more source

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul, Marcel Vančo, Jaroslava Banýrová, Aneta Hujová   +3 more
wiley   +1 more source

Integrating Sexual Health Services Into Primary Care: An Overview of Health Systems Issues and Challenges in Developing Countries

, 2010
Current attempts to address the high burden of sexual health morbidity and mortality in developing countries remain limited in scale due to a range of health system constraints.We conducted a literature review of the policy and programmatic issues that ...
Hawkes, Sarah, Korrie de Koning, Church, Kathryn, Hermen Ormel, Ormel, Hermen, Adriane Martin Hilber, de Koning, Korrie, Hilber, Adriane Martin, Kathryn Church, Sarah Hawkes   +9 more
core   +1 more source

Simplified PCR for detection of Haemophilus ducreyi and diagnosis of chancroid [PDF]

, 1995
A simplified PCR was developed for detection of Haemophilus ducreyi in samples from chancroid patients. The strategy included a straightforward chloroform extraction sample preparation method, a one-tube nested PCR to minimize contamination risks, and a ...
Wilson, S.M, Mabey, DC, Patel, S, Ballard, RC, Changalucha, J, West, B, Mayaud, P   +6 more
core   +4 more sources

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source