Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
ABNORMALITAS KROMOSOM YPADA PENDERITA AMBIGUS GENITALIA Y CHROMOSOME ABNORMALITY IN PATIENTS WITH AMBIGUOUS GENITALIA [PDF]
Background. Ambiguous genitalia is an abnormality signing by the presence of atypical appearance of external genitalia as male or female, or appear as combination of both male and female appearance.
Wasilah , Siti
core +1 more source
Comparative analysis of genitals of Polyommatus boisduvalii (HerrichSchäffer, 1844), P. erotides erotides (Staudinger, 1892) and P. erotides krulikowskyi (Gorbunov, 2001) (Lepidoptera, Lycaenidae) [PDF]
The authors examined male genitalia of several butterflies of Polyommatus eros-group and exhibited steady differences in genital structures between P. erotides krulikowskyi and P. boisduvalii, as well as between P. erotides krulikowskyi and P.
B.V. Stradomsky, O.A. Polumordvinov
doaj +1 more source
microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Ecological and Morphological Studies of Archaeodictyna condocta and Nigma conducens (Araneae: Dictynidae) [PDF]
The morphological and ecological differences between two species of spiders belonging to the family Dictynidae Archaeodictyna condocta and Nigma conducens were studied, and the two species were recorded on citrus and mango trees in Cairo and Giza ...
Doaa Abdel-Ghani
doaj +1 more source
Male genitalia are usually extremely divergent between closely related species, but relatively constant within one species. Here we examine the effect of temperature on the shape of the ventral branches, a male genital structure involved in reproductive ...
Alexandre E. Peluffo +6 more
doaj +1 more source
Nemophora chrysoprasias (Meyrick, 1907), previously known only by the type series from Assam, India, was discovered in the Yunnan Province of China. This study is the first to illustrate the male and female genitalia of N. chrysoprasias.
Toshiya Hirowatari +4 more
doaj +1 more source
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source
A new species of Tetramoera Diakonoff, 1968 (Lepidoptera: Tortricidae) from Japan
Tetramoera yakushimaensis Nasu, sp. nov., is described and illustrated from Japan. The new species is most closely related to T. sasakii Nasu, 2022. The new species brings to 10 the number of described species in the genus.
Yoshitsugu Nasu
doaj +1 more source

