Results 111 to 120 of about 34,011 (232)

Exploration of Half‐Cycle Length of Converging Circular Wavy Duct with Diverging‐Outlet: Turbulent Water Dynamics

open access: yesAdvanced Theory and Simulations, EarlyView.
Increasing half‐cycles intensifies turbulence due to enhanced vortex interactions and flow separation at the diverged‐outlets. Longer wavy ducts are shown to increase flow acceleration, resulting in greater output velocities and more turbulent‐kinetic‐energy production. Wave‐period plays a crucial role in determining turbulent intensity, with amplitude
I. L. Animasaun   +2 more
wiley   +1 more source

DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells

open access: yesAdvanced Science, EarlyView.
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon   +7 more
wiley   +1 more source

CircRNA‐mTOR Promotes Hepatocellular Carcinoma Progression and Lenvatinib Resistance Through the PSIP1/c‐Myc Axis

open access: yesAdvanced Science, EarlyView.
This study verifies that circRNA‐mTOR exhibits high expression levels in HCC and has a strong correlation with patient prognosis. Mechanistically, circRNA‐mTOR achieves this effect by facilitating the nuclear translocation of RNA‐binding protein (RBP) PSIP1 through specific binding.
Yongchang Tang   +12 more
wiley   +1 more source

Profile of patients with genitourinary anomalies treated in a clinical genetics service in the Brazilian unified health system

open access: hybrid, 2015
Ilanna Fragoso Peixoto Gazzaneo   +8 more
openalex   +1 more source

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

open access: yesAdvanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen   +16 more
wiley   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy