Results 191 to 200 of about 49,318 (300)

To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy

European Journal of Haematology, EarlyView.
ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Giovanna Cutrona, Antonella Bruzzese, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Nicola Amodio, Franco Fais, Antonino Neri, Manlio Ferrarini, Valter Gattei, Fortunato Morabito, Massimo Gentile   +16 more
wiley   +1 more source

Very rapid response to belzutifan of VHL-related intracranial and retinal hemangioblastomas. [PDF]

Am J Ophthalmol Case Rep
Pagliara A, De Giuseppe S, Di Profio S, Borzì L, Ramaglia A, Gaggero G, Serafino M, Hadjistilianou D, Molteni M, Mercuri C, Piatelli G, Milanaccio C, Piccolo G, Verrico A.   +13 more
europepmc   +1 more source

World Health Organization classification of tumours of the breast 6th edition 2026

Histopathology, EarlyView.
The 6th edition of the World Health Organization Classification of Breast Tumours introduces changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimes.
Cecily Quinn, Puay Hoon Tan, Kimberly H Allison, Edi Brogi, Sunil R Lakhani, Stuart J Schnitt, Stephen B Fox, Shabnam Jaffer, Aysegul Sahin, Roberto Salgado, Anna Sapino, Ernest Kwasi Adjei, Katherine Geiersbach, Thomas H Helbich, Matteo Lambertini, Christos Sotiriou, Jennelle C Hodge, Joseph D Khoury, Bharat Rekhi, Ales Ryska, Gary Tse, Andrew Field, Harshima Wijesinghe, Pavitratha Puspanathan, Christine Giesen, Blanca Iciar Indave Ruiz, Ian Ellis, Dilani Lokuhetty, WCT Standing Editorial Board, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle C. Hodge, James Kench, Joseph D. Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Mugica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia Sepulveda, Chanjuan Shi, Gary Tse   +47 more
wiley   +1 more source

Corrigendum to Exploring the effects of pharmacological treatments on suicidality in children and adolescents: a structured review of the literature and narrative synthesis eClinicalMedicine Vol 91 January 2026, 103748. [PDF]

EClinicalMedicine
Amerio A, Venturini E, Capanna M, Ploner L, Schiavetti I, Costanza A, Clausi M, Bertuccio P, Odone A, Minnis H, Gajwani R, de Filippis R, De Fazio P, Amore M, Aguglia A, Serafini G.   +15 more
europepmc   +1 more source

Endocervical gastric‐type AIS: a rare histologic finding that further supports the hypothesis of a pyloric‐type metaplastic origin

Histopathology, EarlyView.
Background Gastric‐type adenocarcinoma in situ (gAIS) is a rare, HPV‐independent precursor of cervical adenocarcinoma with incompletely defined histogenesis. Aims To report a case of gAIS and its association with pyloric‐type gastric metaplasia. Materials and Methods A case of gAIS in a 70‐year‐old woman with atypical glandular cells (Pap test) and ...
Michele Paudice, Veronica Parrella, Giulia Scaglione   +2 more
wiley   +1 more source

Correction: Perilli et al. Early Diagnostic Markers in Crisponi Syndrome: Two Cases and Review. <i>J. Clin. Med.</i> 2025, <i>14</i>, 7757. [PDF]

J Clin Med
Perilli L, Dzwilewski K, Pietruszka M, Striano P, Capovilla G, Mazurkiewicz-Bełdzinska M.   +5 more
europepmc   +1 more source

Unveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort

Histopathology, EarlyView.
GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...
Jessica Gasparello, Valentina Angerilli, Mario Domenico Rizzato, Edoardo Maffii, Carlotta Ceccon, Matilde Callegarin, Marianna Sabbadin, Monia Niero, Luisa Toffolatti, Francesca Bergamo, Paola Parente, Luca Mastracci, Federica Grillo, Alessandro Vanoli, Paola Mattiolo, Claudio Luchini, Angelo Paolo Dei Tos, Umberto Cillo, Giacomo Zanus, Sara Lonardi, Matteo Fassan   +20 more
wiley   +1 more source

Redefining Ultrasound's role in early diagnosis of hepatosplenic candidiasis during neutropenia: A pediatric case report in solid tumor. [PDF]

Med Mycol Case Rep
Cappozzo F, Battaglia T, Nebiolo M, Mariani M, Livellara V, Gaggero G, Arkangelskaya E, Damasio MB, Anfigeno L, De Luca C, Avanzini S, Palo F, Conte M, Castagnola E.   +13 more
europepmc   +1 more source

Interventions to Prevent Patient‐ and Visitor‐Perpetrated Violence Against Nurses in the Emergency Department: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To identify interventions and strategies to prevent patient‐ and visitor‐perpetrated violence against nurses working in acute hospital Emergency Departments. Design Scoping review following the Joanna Briggs Institute guidelines. Methods A comprehensive literature search was conducted in PubMed and CINAHL to identify relevant studies ...
Mariarosaria Gammone, Daniela Cattani, Martina Barbieri, Andrea Moro, Milko Zanini, Gianluca Catania, Loredana Sasso, Fiona Timmins, Annamaria Bagnasco   +8 more
wiley   +1 more source

Efficacy of combined JAK1/2 inhibition and cyclosporine in paediatric-onset Still's disease with lung involvement: a case report. [PDF]

Pediatr Rheumatol Online J
Palmeri S, Lancieri M, Ferro J, Salvati P, Cheli M, Papa R, Rosina S, Volpi S, Vellone VG, Ravelli A, Gattorno M, Caorsi R.   +11 more
europepmc   +1 more source