Results 41 to 50 of about 34,426 (254)
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
ExpIR-RO: A Collaborative International Project for Experimenting Voluntary Incident Reporting in the Public Healthcare Sector in Romania [PDF]
"nBackground: Patient safety within healthcare systems is a central aspect of health policy in most developed countries. From April 2007 to May 2009, the pilot project ExpIR-RO tested a voluntary incident reporting system in a public hospital in ...
D Pezzano +7 more
doaj +2 more sources
NiFe‐NO3 Layered Double Hydroxide as a Novel Anode for Sodium Ion Batteries
This study demonstrates, for the first time, the effectiveness of using LDH as an anodic material in SIB. The material is stable and show high specific capacity, the reaction mechanism has been thoroughly investigated and comprehensively described and involves a phase change reaction followed by sodium intercalation.
Marco Fortunato +4 more
wiley +1 more source
The focus of the research carried out by Zones Portuaires and Corpi Idirici for the digital map of Genoa is water. The map is broken down into the theme of the "immersed" with a dual meaning of "invisible underground or underwater'' due to it being ...
Maria Pina Usai +2 more
doaj +1 more source
ABSTRACT Collaborations with nonprofits can enhance firms' legitimacy, yet the relationship between their communication and corporate environmental legitimacy remains poorly understood. Furthermore, research lacks an analysis of the communication of business‐nonprofit collaborations through multiple actors' perspectives.
Andrea Rizzuni +3 more
wiley +1 more source
Reclaiming Anatomy as Method: From Morphological Reasoning to Clinical Relevance
ABSTRACT In recent decades, molecular biology and omics technologies have profoundly reshaped biomedical research, with genomics, proteomics, and other high‐throughput approaches dominating scientific agendas and funding priorities. Within this molecular paradigm, however, the anatomical sciences face an epistemic and institutional tension: morphology,
Katia Cortese, Marco Frascio
wiley +1 more source
A newly synthesized bifunctional azide—diazonium linker allows robust one‐step introduction of azido groups to single‐wall carbon nanotubes. Versatility of the azido groups as reactive handles is demonstrated by further derivatization with 6‐carboxyfluorescein and oligonucleotides.
Razieh Moosavi +6 more
wiley +1 more source
All energy matters Let us broaden the discussion on solutions to climate change. Greenhouse gases have upset the delicate equilibrium of the Earth's energy balance. Consequently, all sources of heat affect the temperature of the Earth. Although the amount of additional heat generated by humans is a fraction of that produced by the sun, it is generated ...
Martin Bertau +2 more
wiley +1 more source
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source
C‐Terminal Tail Elongation Adds a New Dimension to the Tubulin Code
ABSTRACT Tubulin C‐terminal tails undergo diverse post‐translational modifications that regulate microtubule interactions with motors and severing enzymes. TTLL11, a member of the tubulin tyrosine ligase‐like (TTLL) family, uniquely catalyzes glutamate addition to the terminal α‐carboxyl group of both α‐ and β‐primary tubulin tails.
Jana Campbell, Cyril Barinka
wiley +1 more source

