Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]
PLoS Pathogens, 2015 Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Jessica C Jang +11 more
doaj +12 more sources
Helminth genomics: The implications for human health. [PDF]
PLoS Neglected Tropical Diseases, 2009 More than two billion people (one-third of humanity) are infected with parasitic roundworms or flatworms, collectively known as helminth parasites.
Paul J Brindley +3 more
doaj +5 more sources
The tapeworm interactome: inferring confidence scored protein-protein interactions from the proteome of Hymenolepis microstoma [PDF]
BMC Genomics, 2020 Background Reference genome and transcriptome assemblies of helminths have reached a level of completion whereby secondary analyses that rely on accurate gene estimation or syntenic relationships can be now conducted with a high level of confidence ...
Katherine James, Peter D. Olson
doaj +4 more sources
Genetics of helminth infections: Immune system response, insights into host-parasite interaction, and drug resistance [PDF]
Journal of Advanced Veterinary and Animal ResearchHelminthiases, which are caused by parasitic helminths, have a big effect on global health, especially in places with few resources. They cause a lot of illness and put a lot of strain on society and the economy.
Mashael Abdullah Aldamigh
doaj +2 more sources
Three Distinct Circovirids Identified in a Tapeworm Recovered from a Bobcat (Lynx rufus) [PDF]
VirusesBobcats (Lynx rufus) are an iconic North American predator; however, there is limited knowledge regarding their associated parasites. In this case study, we used a metagenomic approach to identify associated viruses and helminth species from a deceased ...
Ayla Žuštra +7 more
doaj +2 more sources
Exploring Genetic Factors Associated with Moniezia spp. Tapeworm Resistance in Central Anatolian Merino Sheep via GWAS Approach [PDF]
AnimalsGastrointestinal parasite (GIP) infections pose significant challenges in pasture-based sheep farming, leading to economic losses and welfare concerns. This study aimed to uncover the genetic basis of resistance to Moniezia spp.
Yunus Arzik +5 more
doaj +2 more sources
Proteomic analysis of the excretory-secretory products from larval stages of Ascaris suum reveals high abundance of glycosyl hydrolases [PDF]
, 2013 Background: Ascaris lumbricoides and Ascaris suum are socioeconomically important and widespread parasites of humans and pigs, respectively. The excretory-secretory (ES) molecules produced and presented at the parasite-host interface during the different
Deforce, Dieter +7 more
core +29 more sources
Population genomics of ancient and modern Trichuris trichiura
Nature Communications, 2022 The whipworm Trichuris trichiura is a soil-transmitted helminth that causes the neglected tropical disease trichuriasis in humans. Here, the authors produce whole genome sequences of modern and ancient samples from humans and non-human primates to ...
Stephen R. Doyle +18 more
doaj +1 more source
Frontiers in Plant Science, 2021 Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases.
Nicolò Alvisi +10 more
doaj +1 more source
Pathogens, 2022 Transmission dynamics and the maintenance of mammarenaviruses in nature are poorly understood. Using metagenomic next-generation sequencing (mNGS) and RT-PCR, we investigated the presence of mammarenaviruses and co-infecting helminths in various tissues ...
Samuel Munalula Munjita +19 more
doaj +1 more source