Results 11 to 20 of about 6,892 (155)

Genomic analyses of aminoacyl tRNA synthetases from human-infecting helminths [PDF]

BMC Genomics, 2019
Helminth infections affect ~ 60% of the human population that lives in tropical and subtropical regions worldwide. These infections result in diseases like schistosomiasis, lymphatic filariasis, river blindness and echinococcosis. Here we provide a comprehensive computational analysis of the aminoacyl tRNA synthetase (aaRS) enzyme family from 27 human ...
Suhel Parvez, Preeti Goel, Preeti Goel, Amit Sharma   +3 more
openaire   +5 more sources

Chromosome-length genome assembly of Teladorsagia circumcincta – a globally important helminth parasite in livestock

BMC Genomics, 2023
Abstract Background Gastrointestinal (GIT) helminthiasis is a global problem that affects livestock health, especially in small ruminants. One of the major helminth parasites of sheep and goats, Teladorsagia circumcincta, infects the abomasum and causes production losses, reductions in weight gain, diarrhoea and, in some
Hassan, Shamshad Ul, Chua, Eng Guan, Paz, Erwin A., Tay, Chin Yen, Greeff, Johan C., Palmer, Dieter G., Dudchenko, Olga, Aiden, Erez Lieberman, Martin, Graeme B., Kaur, Parwinder   +9 more
openaire   +4 more sources

Exploring Genetic Factors Associated with <i>Moniezia</i> spp. Tapeworm Resistance in Central Anatolian Merino Sheep via GWAS Approach. [PDF]

Animals (Basel)
Gastrointestinal parasite (GIP) infections pose significant challenges in pasture-based sheep farming, leading to economic losses and welfare concerns. This study aimed to uncover the genetic basis of resistance to Moniezia spp.
Arzik Y, Kizilaslan M, Behrem S, Piel LMW, White SN, Çınar MU.   +5 more
europepmc   +2 more sources

Revealing the associated microflora hosted by the globally significant parasite Trichostrongylus colubriformis. [PDF]

Sci Rep
Trichostrongylus colubriformis is a parasitic helminth that primarily infects small ruminants, causing substantial economic losses in the livestock industry. Exploring the microbiome of this helminth might provide insights into the potential influence of
Paz EA, Chua EG, Palmer DG, Greeff JC, Liu S, Cheuquemán C, Hassan SU, Martin GB, Tay CY.   +8 more
europepmc   +2 more sources

Population genomics of ancient and modern Trichuris trichiura

Nature Communications, 2022
The whipworm Trichuris trichiura is a soil-transmitted helminth that causes the neglected tropical disease trichuriasis in humans. Here, the authors produce whole genome sequences of modern and ancient samples from humans and non-human primates to ...
Stephen R. Doyle, Martin Jensen Søe, Peter Nejsum, Martha Betson, Philip J. Cooper, Lifei Peng, Xing-Quan Zhu, Ana Sanchez, Gabriela Matamoros, Gustavo Adolfo Fontecha Sandoval, Cristina Cutillas, Louis-Albert Tchuem Tchuenté, Zeleke Mekonnen, Shaali M. Ame, Harriet Namwanje, Bruno Levecke, Matthew Berriman, Brian Lund Fredensborg, Christian Moliin Outzen Kapel   +18 more
doaj   +1 more source

β-Hexosaminidases Along the Secretory Pathway of Nicotiana benthamiana Have Distinct Specificities Toward Engineered Helminth N-Glycans on Recombinant Glycoproteins

Frontiers in Plant Science, 2021
Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases.
Nicolò Alvisi, Kim van Noort, Sarlita Dwiani, Nathan Geschiere, Octavina Sukarta, Koen Varossieau, Dieu-Linh Nguyen, Richard Strasser, Cornelis H. Hokke, Arjen Schots, Ruud H. P. Wilbers   +10 more
doaj   +1 more source

Luna Virus and Helminths in Wild Mastomys natalensis in Two Contrasting Habitats in Zambia: Risk Factors and Evidence of Virus Dissemination in Semen

Pathogens, 2022
Transmission dynamics and the maintenance of mammarenaviruses in nature are poorly understood. Using metagenomic next-generation sequencing (mNGS) and RT-PCR, we investigated the presence of mammarenaviruses and co-infecting helminths in various tissues ...
Samuel Munalula Munjita, Given Moonga, Andrew Nalishuwa Mukubesa, Joseph Ndebe, Benjamin Mubemba, Manu Vanaerschot, Cristina Tato, John Tembo, Nathan Kapata, Simbarashe Chitanga, Katendi Changula, Mashiro Kajihara, Walter Muleya, Ayato Takada, Elisabeth Fichet-Calvet, Alimuddin Zumla, Hirofumi Sawa, Matthew Bates, Sody Munsaka, Edgar Simulundu   +19 more
doaj   +1 more source

Impact of intestinal parasites on microbiota and cobalamin gene sequences: a pilot study

Parasites & Vectors, 2020
Background Approximately 30% of children worldwide are infected with gastrointestinal parasites. Depending on the species, parasites can disrupt intestinal bacterial microbiota affecting essential vitamin biosynthesis.
Rojelio Mejia, Ashish Damania, Rebecca Jeun, Patricia E. Bryan, Paola Vargas, Marisa Juarez, Pamela S. Cajal, Julio Nasser, Alejandro Krolewiecki, Emilie Lefoulon, Courtney Long, Evan Drake, Rubén O. Cimino, Barton Slatko   +13 more
doaj   +1 more source

Transgenesis in parasitic helminths: a brief history and prospects for the future

Parasites & Vectors, 2022
Helminth infections impact the health of hundreds of millions of persons globally and also cause important economic losses in livestock farming. Methodological limitations as well as the low attention given to the study of helminths have impacted ...
M. J. Quinzo, M. J. Perteguer, P. J. Brindley, A. Loukas, J. Sotillo   +4 more
doaj   +1 more source

Genome-Wide Analyses of Individual Strongyloides stercoralis (Nematoda: Rhabditoidea) Provide Insights into Population Structure and Reproductive Life Cycles. [PDF]

PLoS Neglected Tropical Diseases, 2016
The helminth Strongyloides stercoralis, which is transmitted through soil, infects 30-100 million people worldwide. S. stercoralis reproduces sexually outside the host as well as asexually within the host, which causes a life-long infection.
Taisei Kikuchi, Akina Hino, Teruhisa Tanaka, Myo Pa Pa Thet Hnin Htwe Aung, Tanzila Afrin, Eiji Nagayasu, Ryusei Tanaka, Miwa Higashiarakawa, Kyu Kyu Win, Tetsuo Hirata, Wah Win Htike, Jiro Fujita, Haruhiko Maruyama   +12 more
doaj   +1 more source