Results 21 to 30 of about 6,892 (155)
The landscape of human genes involved in the immune response to parasitic worms
BMC Evolutionary Biology, 2010 Background More than 2 billion individuals worldwide suffer from helminth infections. The highest parasite burdens occur in children and helminth infection during pregnancy is a risk factor for preterm delivery and reduced birth weight.
Fumagalli Matteo +6 more
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Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors. [PDF]
PLoS Neglected Tropical Diseases, 2016 Helminth parasites rely on fast-synaptic transmission in their neuromusculature to experience the outside world and respond to it. Acetylcholine plays a pivotal role in this and its receptors are targeted by a wide variety of both natural and synthetic ...
Thomas B Duguet +6 more
doaj +1 more source
Genome-wide identification and characterization of eukaryotic protein kinases
Frontiers in Bioscience-Landmark, 2020 The tropical liver fluke, Fasciola gigantica is a food-borne parasite responsible for the hepatobiliary disease fascioliasis. The recent completion of F.
Kanhu Charan Das +2 more
doaj +1 more source
Frontiers in Genetics, 2019 Whole-genome sequencing is being rapidly applied to the study of helminth genomes, including de novo genome assembly, population genetics, and diagnostic applications.
Stephen R. Doyle +28 more
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Communications Biology, 2021 Wang and colleagues report a high quality draft genome for the thin-necked bladder worm, an agricultural livestock parasitic pest. Using this draft genome and comparison with other related parasites, they reveal gene families that are selectively ...
Shuai Wang +11 more
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Parasites & Vectors, 2018 Background The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths.
James E. Wright +3 more
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Improving helminth genome resources in the post-genomic era
Trends in Parasitology, 2022 Rapid advancement in high-throughput sequencing and analytical approaches has seen a steady increase in the generation of genomic resources for helminth parasites. Now, helminth genomes and their annotations are a cornerstone of numerous efforts to compare genetic and transcriptomic variation, from single cells to populations of globally distributed ...
openaire +2 more sources
PLoS Pathogens, 2015 Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Jessica C Jang +11 more
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Helminths and Cancers From the Evolutionary Perspective
Frontiers in Medicine, 2018 Helminths include free-living and parasitic Platyhelminthes and Nematoda which infect millions of people worldwide. Some Platyhelminthes species of blood flukes (Schistosoma haematobium, Schistosoma japonicum, and Schistosoma mansoni) and liver flukes ...
Larissa L. S. Scholte +5 more
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Frontiers in Genetics, 2020 Haemonchus contortus and Teladorsagia circumcincta are among the two most pathogenic internal parasitic nematodes infecting small ruminants, such as sheep and goats, and are a global animal health issue.
Nikola Palevich +3 more
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