Results 31 to 40 of about 16,403 (216)
Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams +101 more
core +1 more source
Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]
Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A. +2 more
core +3 more sources
Improving helminth genome resources in the post-genomic era
Rapid advancement in high-throughput sequencing and analytical approaches has seen a steady increase in the generation of genomic resources for helminth parasites. Now, helminth genomes and their annotations are a cornerstone of numerous efforts to compare genetic and transcriptomic variation, from single cells to populations of globally distributed ...
openaire +2 more sources
Genome-wide identification and characterization of eukaryotic protein kinases
The tropical liver fluke, Fasciola gigantica is a food-borne parasite responsible for the hepatobiliary disease fascioliasis. The recent completion of F.
Kanhu Charan Das +2 more
doaj +1 more source
Wang and colleagues report a high quality draft genome for the thin-necked bladder worm, an agricultural livestock parasitic pest. Using this draft genome and comparison with other related parasites, they reveal gene families that are selectively ...
Shuai Wang +11 more
doaj +1 more source
The Echinococcus canadensis (G7) genome: A key knowledge of parasitic platyhelminth human diseases [PDF]
Background: The parasite Echinococcus canadensis (G7) (phylum Platyhelminthes, class Cestoda) is one of the causative agents of echinococcosis. Echinococcosis is a worldwide chronic zoonosis affecting humans as well as domestic and wild mammals, which ...
A Bankevich +109 more
core +8 more sources
Background The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths.
James E. Wright +3 more
doaj +1 more source
What helminth genomes have taught us about parasite evolution [PDF]
SUMMARYThe genomes of more than 20 helminths have now been sequenced. Here we perform a meta-analysis of all sequenced genomes of nematodes and Platyhelminthes, and attempt to address the question of what are the defining characteristics of helminth genomes.
Zarowiecki, Magdalena, Berriman, Matt
openaire +3 more sources
Helminths and Cancers From the Evolutionary Perspective
Helminths include free-living and parasitic Platyhelminthes and Nematoda which infect millions of people worldwide. Some Platyhelminthes species of blood flukes (Schistosoma haematobium, Schistosoma japonicum, and Schistosoma mansoni) and liver flukes ...
Larissa L. S. Scholte +5 more
doaj +1 more source
Haemonchus contortus and Teladorsagia circumcincta are among the two most pathogenic internal parasitic nematodes infecting small ruminants, such as sheep and goats, and are a global animal health issue.
Nikola Palevich +3 more
doaj +1 more source

