Results 51 to 60 of about 6,892 (155)

Genetics of helminth infections: Immune system response, insights into host-parasite interaction, and drug resistance

Journal of Advanced Veterinary and Animal Research
Helminthiases, which are caused by parasitic helminths, have a big effect on global health, especially in places with few resources. They cause a lot of illness and put a lot of strain on society and the economy.
Mashael Abdullah Aldamigh
doaj   +1 more source

A Catch‐Release Strategy for the Genomics‐Driven Discovery of Antiproliferative Furan‐Functionalized Peptides

Angewandte Chemie, Volume 137, Issue 11, March 10, 2025.
A streamlined strategy for the discovery and isolation of pharmacologically relevant furan‐containing nonribosomal peptides is presented. Genome mining prioritizes microbes harboring specialized 3‐furylalanine (Fua) synthases, and a reversible Fua Diels–Alder reaction enables the rapid and selective discovery and resin‐based purification of Fua‐bearing
Friedrich J. Ehinger, Kirstin Scherlach, Felix Trottmann, Jonas Fiedler, Ingrid Richter, Christian Hertweck   +5 more
wiley   +2 more sources

Potential Zoonotic Infections Transmitted by Free‐Ranging Macaques in Human–Monkey Conflict Areas in Thailand

Zoonoses and Public Health, Volume 72, Issue 4, Page 349-358, June 2025.
ABSTRACT Introduction Nonhuman primates (NHPs) can transmit zoonotic diseases to humans because of their close genetic relationship, facilitating the cross‐species transmission of certain pathogens. In Thailand, Macaca is the most common NHP genus and their inhabits area are in close proximity of human, particularly in urban and suburban areas, where ...
Sarin Suwanpakdee, Benjaporn Bhusri, Aeknarin Saechin, Chalisa Mongkolphan, Siriporn Tangsudjai, Parut Suksai, Supakarn Kaewchot, Rattana Sariwongchan, Piya Sereerak, Ladawan Sariya   +9 more
wiley   +1 more source

Heavy Metal Pollution From Illegal Mining ‘Galamsey’ Activities on the Viability of Clarias gariepinus in the Oda River, Ghana

Aquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.
ABSTRACT Activities associated with illegal mining, ‘galamsey’, often result in significant environmental degradation, particularly to water bodies. In the case of River Oda, like all other affected areas in Ghana, galamsey operations contribute to the pollution of the water body with some heavy metals such as mercury (Hg), cadmium (Cd) and arsenic (As)
Seth Adusei, Emmanuel Kwesi Arthur, Emmanuel Gikunoo, William Amponsah, Frank Ofori Agyemang, Godfred Ohemeng‐Boahen   +5 more
wiley   +1 more source

HIV protease inhibitor nelfinavir is a potent drug candidate against echinococcosis by targeting Ddi1-like protein

EBioMedicine, 2022
Summary: Background: Alveolar echinococcosis (AE), which is caused by larval Echinococcus multilocularis, is one of the world's most dangerous neglected diseases. Currently, no fully effective treatments are available to cure this disease.
Zhongli Liu, Xiaola Guo, Aijiang Guo, Shengying Zhang, Yang Zou, Yugui Wang, Xiaolu Li, Wei He, Lixia Pu, Shaohua Zhang, Qiaoying Zeng, Xuepeng Cai, Shuai Wang   +12 more
doaj  

The tapeworm interactome: inferring confidence scored protein-protein interactions from the proteome of Hymenolepis microstoma

BMC Genomics, 2020
Background Reference genome and transcriptome assemblies of helminths have reached a level of completion whereby secondary analyses that rely on accurate gene estimation or syntenic relationships can be now conducted with a high level of confidence ...
Katherine James, Peter D. Olson
doaj   +1 more source

Comparison of multi-parallel quantitative real-time PCRs targeting different DNA regions and detecting soil-transmitted helminths in stool. [PDF]

Parasit Vectors
Background Soil-transmitted helminths infect an estimated 18% of the world’s population, causing a significant health burden. Microscopy has been the primary tool for diagnosing eggs from fecal samples, but its sensitivity drops in low-prevalence ...
Papaiakovou M, Cimino RO, Pilotte N, Dunn J, Littlewood DTJ, Williams SA, Krolewiecki AJ, Mejia R.   +7 more
europepmc   +2 more sources

Genomic investigations of successful invasions: the picture emerging from recent studies

Biological Reviews, Volume 100, Issue 3, Page 1396-1418, June 2025.
ABSTRACT Invasion biology aims to identify traits and mechanisms that contribute to successful invasions, while also providing general insights into the mechanisms underlying population expansion and adaptation to rapid climate and habitat changes. Certain phenotypic attributes have been linked to successful invasions, and the role of genetics has been
Joanna Kołodziejczyk, Anna Fijarczyk, Ilga Porth, Piotr Robakowski, Noel Vella, Adriana Vella, Agnieszka Kloch, Aleksandra Biedrzycka   +7 more
wiley   +1 more source

Long-read RNA sequencing of human and animal filarial parasites improves gene models and discovers operons.

PLoS Neglected Tropical Diseases, 2020
Filarial parasitic nematodes (Filarioidea) cause substantial disease burden to humans and animals around the world. Recently there has been a coordinated global effort to generate, annotate, and curate genomic data from nematode species of medical and ...
Nicolas J Wheeler, Paul M Airs, Mostafa Zamanian   +2 more
doaj   +1 more source

Machine learning models accurately predict clades of proteocephalidean tapeworms (Onchoproteocephalidea) based on host and biogeographical data

Cladistics, Volume 41, Issue 3, Page 264-282, June 2025.
Abstract Proteocephalids are a cosmopolitan and diverse group of tapeworms (Cestoda) that have colonized vertebrate hosts in freshwater and terrestrial environments. Despite the ubiquity of the group, key macroevolutionary processes that have driven the group's evolution have yet to be identified.
Philippe Vieira Alves, Reinaldo José da Silva, Tomáš Scholz, Alain de Chambrier, José Luis Luque, Anastasiia Duchenko, Daniel Janies, Denis Jacob Machado   +7 more
wiley   +1 more source