Results 61 to 70 of about 16,403 (216)
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
BMC Genomics, 2009 Background Schistosomes are trematode parasites of the phylum Platyhelminthes. They are considered the most important of the human helminth parasites in terms of morbidity and mortality.
Santana Clara +8 more
doaj +1 more source
Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges
Advanced Science, Volume 13, Issue 5, 27 January 2026.This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li +7 more
wiley +1 more source
Transcriptome analysis of Taenia solium cysticerci using Open reading Frame ESTS (ORESTES) [PDF]
, 2009 Background Human infection by the pork tapeworm Taenia solium affects more than 50 million people worldwide, particularly in underdeveloped and developing countries. Cysticercosis which arises from larval encystation can be life threatening and difficult
Almeida, Carolina R. +15 more
core +3 more sources
Specialized Dendritic Cells Mediating Peripheral Tolerance to Intestinal Antigens
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT The immune system is tasked with mounting effective responses to pathogens while preventing inflammation triggered by innocuous antigens, including those derived from self, food, and commensal microbes. This balance is especially critical in the intestine, where dietary and microbial antigens are constantly encountered.
Liuhui Fu, Dan R. Littman
wiley +1 more source
Advances in the study of helminth mitochondrial genomes and their associated applications [PDF]
Chinese Science Bulletin, 2012 Helminths, including flatworms and roundworms, are abundant organisms that have a variety of life histories. Of these, the genera Schistosoma, Echinococcus, Trichinella are notable parasites of veterinary and medical importance, and cause substantial socioeconomic losses throughout China and the rest of the world.
Jia, WanZhong +6 more
openaire +1 more source
In silico design of a T-cell epitope vaccine candidate for parasitic helminth infection.
PLoS Pathogens, 2020 Trichuris trichiura is a parasite that infects 500 million people worldwide, leading to colitis, growth retardation and Trichuris dysentery syndrome. There are no licensed vaccines available to prevent Trichuris infection and current treatments are of ...
Ayat Zawawi +8 more
doaj +1 more source
Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]
, 2019 Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V. +10 more
core +3 more sources
The Microbiome Within a Microbe: Rethinking Blastocystis Biology
Journal of Eukaryotic Microbiology, Volume 73, Issue 1, January/February 2026.ABSTRACT Blastocystis spp., one of the most prevalent microeukaryotes in the human gut, has long puzzled researchers with its ambiguous role in health and disease. Decades‐old microscopy studies reported bacterial‐ and viral‐like particles within Blastocystis spp. cells, but these findings have been mainly overlooked.
Daisy Shaw +2 more
wiley +1 more source
Improving Prediction of Helminth Aminoacyl‐tRNA Synthetases through Manual Analysis of Genomic Data
The FASEB Journal, 2021 Helminth is a generic term for the parasitic worms that negatively impact health outcomes for a roughly a quarter of the global population. Although more than 150 helminth genomes have now been sequenced, protein sequence predictions available in compiled genomes and public databases are often incorrect. These errors hinder identification of novel drug
Alison Block +5 more
openaire +1 more source