Results 71 to 80 of about 6,892 (155)

Molecular Characterization and Analysis of Human Trichostrongylus Species in an Endemic Region of Iran Based on COX 1 Gene; A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Trichostrongylus species are the causative agents of zoonotic disease, which has been frequently reported from animals in Iran. The aim of this study was to identify, molecular characterization and analysis of Trichostrongylus species isolated from humans, in an endemic region, based on cytochrome c oxidase (COX) 1 ...
Sara Nemati, Hanieh Mohammad Rahimi, Meysam Sharifdini, Hamed Mirjalali   +3 more
wiley   +1 more source

Editorial: Novel Frontiers in Helminth Genomics [PDF]

Frontiers in Genetics, 2020
Gabriel Rinaldi, Makedonka Mitreva, José F. Tort, Klaus Brehm   +3 more
openaire   +3 more sources

A Spotlight on Archaea in Humans, Livestock and Poultry: A Review

Veterinary Medicine and Science, Volume 11, Issue 2, March 2025.
The microbiota includes prokaryotes (archaea and bacteria) and eukaryotes. Archaea are single‐celled prokaryotes and essential part of gut microbiome. Researches on archaea in ruminants and humans are more than mono‐gastric. The low abundance of archaea in the gut depends on the method used (metagenomics or meta‐transcriptomic) and age of people or ...
Ahmad Salahi, Wafaa A. Abd El‐Ghany
wiley   +1 more source

Evidence of selection as a cause for racial disparities in fibroproliferative disease.

PLoS ONE, 2017
Fibroproliferative diseases are common complex traits featuring scarring and overgrowth of connective tissue which vary widely in presentation because they affect many organ systems.
Jacklyn N Hellwege, Eric S Torstenson, Shirley B Russell, Todd L Edwards, Digna R Velez Edwards   +4 more
doaj   +1 more source

Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni

Parasites & Vectors, 2015
Background Drug discovery for the neglected tropical disease schistosomiasis has a high priority. Anticancer drugs, especially protein kinase inhibitors, might serve as a starting point for drug discovery owing to the importance of protein kinases in ...
Noemi Cowan, Jennifer Keiser
doaj   +1 more source

Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype

Frontiers in Immunology, 2018
Hepatic macrophages play an essential role in the granulomatous response to infection with the parasitic helminth Schistosoma mansoni, but the transcriptional changes that underlie this effect are poorly understood.
Diana Cortes-Selva, Andrew F. Elvington, Andrew F. Elvington, Andrew Ready, Bartek Rajwa, Edward J. Pearce, Gwendalyn J. Randolph, Keke C. Fairfax, Keke C. Fairfax   +8 more
doaj   +1 more source

The Schistosoma mansoni phylome: using evolutionary genomics to gain insight into a parasite’s biology

BMC Genomics, 2012
Background Schistosoma mansoni is one of the causative agents of schistosomiasis, a neglected tropical disease that affects about 237 million people worldwide.
Silva Larissa, Marcet-Houben Marina, Nahum Laila, Zerlotini Adhemar, Gabaldón Toni, Oliveira Guilherme   +5 more
doaj   +1 more source

The genetic basis of adaptive evolution in parasitic environment from the Angiostrongylus cantonensis genome.

PLoS Neglected Tropical Diseases, 2019
Angiostrongylus cantonensis (rat lungworm) is the etiological agent of angiostrongyliasis, mainly causing eosinophilic meningitis or meningoencephalitis in human. Although the biology of A. cantonensis is relatively well known, little is understood about
Lian Xu, Meng Xu, Xi Sun, Junyang Xu, Xin Zeng, Dai Shan, Dongjuan Yuan, Ping He, Weiming He, Yulan Yang, Shiqi Luo, Jie Wei, Xiaoying Wu, Zhen Liu, Xiaomin Xu, Zhensheng Dong, Langui Song, Beibei Zhang, Zilong Yu, Lifu Wang, Chi Zhang, Xiaodong Fang, Qiang Gao, Zhiyue Lv, Zhongdao Wu   +24 more
doaj   +1 more source

Cystatin from the helminth Ascaris lumbricoides upregulates mevalonate and cholesterol biosynthesis pathways and immunomodulatory genes in human monocyte-derived dendritic cells

Frontiers in Immunology
BackgroundAscaris lumbricoides cystatin (Al-CPI) prevents the development of allergic airway inflammation and dextran-induced colitis in mice models. It has been suggested that helminth-derived cystatins inhibit cathepsins in dendritic cells (DC), but ...
Nathalie Acevedo, Ana Lozano, Josefina Zakzuk, Kevin Llinás-Caballero, David Brodin, Peter Nejsum, Andrew R. Williams, Luis Caraballo   +7 more
doaj   +1 more source

Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods.

PLoS Neglected Tropical Diseases, 2019
BackgroundPreventive chemotherapy (PC) with benzimidazole drugs is the backbone of soil-transmitted helminth (STH) control programs. Over the past decade, drug coverage has increased and with it, the possibility of developing anthelmintic resistance.
Johnny Vlaminck, Piet Cools, Marco Albonico, Shaali Ame, Mio Ayana, Giuseppe Cringoli, Daniel Dana, Jennifer Keiser, Maria P Maurelli, Leonardo F Matoso, Antonio Montresor, Zeleke Mekonnen, Greg Mirams, Rodrigo Corrêa-Oliveira, Simone A Pinto, Laura Rinaldi, Somphou Sayasone, Eurion Thomas, Jozef Vercruysse, Jaco J Verweij, Bruno Levecke   +20 more
doaj   +1 more source