Results 291 to 300 of about 3,155,630 (345)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Genome-wide association study of economic traits and functional characterization of MAN2A2 in the Jilin White Goose. [PDF]

Poult Sci
Song Y, Ma J, Mabrouk I, Liu Q, Hua G, Ma X, Xu J, Cao H, Wang J, Li J, Liu J, Zhang J, Zhang X, Sun Y.   +13 more
europepmc   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Genetic and clinical determinants of neonatal jaundice and growth patterns in the Qingdao birth cohort: A genome-wide association study. [PDF]

PLoS One
Chen X, Du P, Li S, Wang X, Xu M, Chu Z, Zhang Y, Yao Z, Huan X, Huang Y, Fang M, Gao Y, Fan G, Jin X, Huang H, Pan S.   +15 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Genome-wide association study of pediatric bacteremia and sepsis

Lawless D, Hodel FA, Thorball CW, Xu ZM, Borghesi A, Giannoni E, Trück J, Stocker M, Posfay-Barbe KM, Heininger U, Bernhard-Stirnemann S, Niederer-Loher A, Kahlert CR, Natalucci G, Relly C, Berger C, Riedel T, Aebi C, Agyeman P, Fellay J, Schlapbach LJ.   +20 more
europepmc   +1 more source

Genome-wide association study of Asian women identifies putative mammographic density-associated loci. [PDF]

Breast Cancer Res
Mariapun S, Eriksson M, Tai MC, Mohd Taib NA, Yip CH, Rahmat K, Vachon CM, Lindstrom S, Li J, Hartman M, Hall P, Easton DF, Ho WK, Teo SH.   +13 more
europepmc   +1 more source

Genome wide association study for production traits in canchim breed. [PDF]

, 2015
BLECHA, I. M. Z., CARDOSO, F. F., FERREIRA, A. B. R., GARCIA, J. F., REGITANO, L. C. de A., SANTIAGO, G. G., SIQUEIRA, F., SOUZA JÚNIOR, M. D., TORRES JUNIOR, R. A. de A.   +8 more
core  

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda, Hyo‐Min Kim, Nicole Battaglia, Joshua Rong, Amy Tam, Enrique Gonzalez Saez‐Diez, Cornelius F. Boerkoel, Afshin Saffari, Vicente Quiroz, Luca Schierbaum, Zainab Zaman, Katerina Bernardi, Darius Ebrahimi‐Fakhari   +12 more
wiley   +1 more source

Genome-wide association study (GWAS) identifies genetic loci controlling Distinctness, Uniformity, and Stability (DUS) traits in wheat. [PDF]

Theor Appl Genet
Zanella CM, Horsnell R, Love B, Wright TIC, Taferner-Kriegl J, Flamm C, Andreani L, Delogu C, McMillan V, Wallace M, Scott E, Cockram J.   +11 more
europepmc   +1 more source