Results 271 to 280 of about 669,401 (295)

Validation of a Genetic Risk Score Combined with Clinical Variables for Predicting Pulmonary Fibrosis in early Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objectives Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). The study aimed to externally validate a genetic risk score (GRS) and a combined risk score for predicting the risk of RA‐associated PF in an independent cohort of early‐RA patients. Methods This study utilized an inception cohort of 1118 patients
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Genetic Architecture of Ischemic Stroke: Insights from Genome-Wide Association Studies and Beyond. [PDF]

J Cardiovasc Dev Dis
Jagodic A, Zivalj D, Krsek A, Baticic L.
europepmc   +1 more source

Genome-Wide Association Study and Functional Validation of CsAGD6 Conferring Drought Tolerance in Tea Plant

Jiaxuan Yue, Shan He, Shicai Liang, Yu Wang, Huan Wang, Xuxu Lang, Kai Fan, Jianhui Hu, Jiazhi Shen, Litao Sun, Shibo Ding, Zhaotang Ding, Wenjun Qian   +12 more
openalex   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

Arthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Editorial: Advancements and prospects of genome-wide association studies. [PDF]

Front Genet
Doumatey AP, Li Y, Fernandez-Lopez JC.
europepmc   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Genetic dissection of gluten characteristics based on single- and multi-locus genome-wide association studies in wheat (<i>Triticum aestivum</i> L.). [PDF]

Food Chem (Oxf)
Jiang X, Li Q, Geng Y, Zhao J, Li Y, Li H.   +5 more
europepmc   +1 more source

Understanding the genetic basis of heat stress tolerance in wheat (Triticum aestivum L.) through genome-wide association studies. [PDF]

Plant Genome
Gudi S, Singh J, Gill H, Sehgal S, Faris JD, Gill U, Gupta R.   +6 more
europepmc   +1 more source

Genome-wide association studies on body-weight and body-size traits among Zhedong white geese based on a modified genotyping-by-sequencing method. [PDF]

BMC Genomics
Yang Y, Zhai S, Liu H, Wang H, He D.
europepmc   +1 more source

The Impact of Ancestry on Genome-Wide Association Studies. [PDF]

Pac Symp Biocomput
Jones SC, Cardone KM, Bradford Y, Tishkoff SA, Ritchie MD.   +4 more
europepmc   +1 more source