Results 201 to 210 of about 1,111,517 (383)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Assessing the Causal Impact of Social Isolation on Angina Risk: Evidence from a Two-Sample Mendelian Randomization Study

Journal of Multidisciplinary Healthcare
Shenghua Yan,1,* Feifei Gu,2,* Bei Tian1,2 1Shanghai University of Traditional Chinese Medicine (SHUTCM), Shanghai, 201203, People’s Republic of China; 2Department of Nursing, Shanghai Pudong New Area Zhoupu Hospital (Shanghai Health Medical ...
Yan S, Gu F, Tian B
doaj  

MOESM1 of Eigen decomposition expedites longitudinal genome-wide association studies for milk production traits in Chinese Holstein

, 2018
Chao Ning, Dan Wang, Xianrui Zheng, Qin Zhang, Shengli Zhang, Raphael Mrode, Jianfeng Liu   +6 more
openalex   +1 more source

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis [PDF]

, 2016
Puya Gharahkhani, Rebecca C. Fitzgerald, Thomas L. Vaughan, Claire Palles, Ines Gockel, Ian Tomlinson, Matthew F. Buas, Andrea May, Christian Gerges, Mario Anders, Jessica Becker, Nicole Kreuser, Tania Noder, Marino Venerito, Lothar Veits, Thomas Schmidt, Hendrik Manner, Clemens Schmidt, Timo Hess, Anne C. Böhmer, Jakob R. Izbicki, Arnulf H. Hölscher, Hauke Lang, Dietmar Lorenz, Brigitte Schumacher, Andreas Hackelsberger, Rupert Mayershofer, Oliver Pech, Yogesh K. Vashist, Katja Ott, Michael Vieth, Josef Weismüller, Markus M. Nöthen, Stephen E. Attwood, Hugh Barr, Laura Chegwidden, John de Caestecker, Rebecca Harrison, Sharon Love, David MacDonald, Paul Moayyedi, Hans Prenen, R. G. P. Watson, Prasad G. Iyer, Lesley Anderson, Leslie Bernstein, Wong‐Ho Chow, Laura J. Hardie, Jesper Lagergren, Geoffrey Liu, Harvey A. Risch, Anna H. Wu, Weimin Ye, Nigel C. Bird, Nicholas J. Shaheen, Marilie D. Gammon, Douglas A. Corley, Carlos Caldas, Susanne Moebus, Michael Knapp, Wilbert H.M. Peters, Horst Neuhaus, Thomas Rösch, Christian Ell, Stuart MacGregor, Paul D.P. Pharoah, David C. Whiteman, Janusz Jankowski, Johannes Schumacher   +68 more
openalex   +1 more source

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Nature Genetics, 2009
J. Lambert, S. Heath, G. Even, D. Campion, K. Sleegers, M. Hiltunen, O. Combarros, D. Zélénika, M. Bullido, B. Tavernier, L. Letenneur, K. Bettens, C. Berr, F. Pasquier, N. Fievet, P. Barberger‐Gateau, S. Engelborghs, P. Deyn, I. Mateo, A. Franck, S. Helisalmi, E. Porcellini, O. Hanon, M. Pancorbo, C. Lendon, C. Dufouil, C. Jaillard, T. Léveillard, V. Álvarez, P. Bosco, M. Mancuso, F. Panza, B. Nacmias, P. Bossù, P. Piccardi, G. Annoni, D. Seripa, D. Galimberti, D. Hannequin, F. Licastro, H. Soininen, K. Ritchie, H. Blanché, J. Dartigues, C. Tzourio, I. Gut, C. Broeckhoven, A. Alpérovitch, M. Lathrop, P. Amouyel   +49 more
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Genome-wide Association Studies and Genes for Seed Germination Chromosome under Low-Temperature Stress in Maize (<i>Zea mays</i> L) Cropping System [PDF]

, 2023
Xiaofen Li, Rongzhen Wang, Kaiyuan Cui, Hafeeze Noor, Pengcheng Ding, Fida Noor   +5 more
openalex   +1 more source

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

Nature Genetics, 2020
K. Ishigaki, M. Akiyama, M. Kanai, A. Takahashi, Eiryo Kawakami, Hiroki Sugishita, S. Sakaue, N. Matoba, Siew-Kee Low, Y. Okada, C. Terao, Tiffany Amariuta, S. Gazal, Y. Kochi, M. Horikoshi, Ken Suzuki, K. Ito, S. Koyama, K. Ozaki, S. Niida, Yasushi Sakata, Yasuhiko Sakata, T. Kohno, K. Shiraishi, Y. Momozawa, M. Hirata, K. Matsuda, M. Ikeda, N. Iwata, S. Ikegawa, I. Kou, Toshihiro Tanaka, H. Nakagawa, A. Suzuki, T. Hirota, M. Tamari, K. Chayama, D. Miki, Masaki Mori, S. Nagayama, Y. Daigo, Y. Miki, T. Katagiri, O. Ogawa, W. Obara, Hidemi Ito, Teruhiko Yoshida, I. Imoto, Takashi Takahashi, C. Tanikawa, Takao Suzuki, N. Sinozaki, S. Minami, H. Yamaguchi, S. Asai, Yasuo Takahashi, K. Yamaji, Kazuhisa Takahashi, T. Fujioka, R. Takata, H. Yanai, A. Masumoto, Y. Koretsune, H. Kutsumi, M. Higashiyama, S. Murayama, N. Minegishi, Kichiya Suzuki, K. Tanno, A. Shimizu, T. Yamaji, M. Iwasaki, N. Sawada, H. Uemura, Keitaro Tanaka, M. Naito, Makoto Sasaki, K. Wakai, S. Tsugane, Masayuki Yamamoto, Kazuhiko Yamamoto, Y. Murakami, Yusuke Nakamura, S. Raychaudhuri, J. Inazawa, T. Yamauchi, T. Kadowaki, M. Kubo, Y. Kamatani   +88 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Genome-wide association study of anterior uveitis [PDF]

Fredrika Koskimäki, Oona Ahokas, Abdelrahman G. Elnahas, Anu Reigo, Kadri Reis, Tōnu Esko, Priit Palta, Sanna Leinonen, Johannes Kettunen, Johanna Liinamaa, Minna K. Karjalainen, Ville Saarela   +11 more
openalex   +1 more source