Results 211 to 220 of about 850,713 (297)

A new association test based on disease allele selection for case–control genome-wide association studies [PDF]

, 2014
Zhongxue Chen
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Genome-Wide Association Study for Milk Protein Content in Romanian Dual-Purpose Cattle. [PDF]

Life (Basel)
Bratu DG, Blaga Ș, Zanfira BC, Mircu C, Spătaru II, Torda I, Mizeranschi AE, Ilie DE, Cziszter LT, Vizitiu DA, Boldura OM, Huțu I.   +11 more
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Genome-wide association study of Asian women identifies putative mammographic density-associated loci. [PDF]

Breast Cancer Res
Mariapun S, Eriksson M, Tai MC, Mohd Taib NA, Yip CH, Rahmat K, Vachon CM, Lindstrom S, Li J, Hartman M, Hall P, Easton DF, Ho WK, Teo SH.   +13 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Genome-wide association study identifies quantitative trait loci associated with resistance to Verticillium dahliae race 3 in tomato. [PDF]

Plant Genome
Adhikari TB, Olukolu BA, Pandey A, Philbrick AN, Panthee DR, Shekasteband R, Gardner RG, Dean RA, Louws FJ.   +8 more
europepmc   +1 more source

Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population

, 2009
Masakazu Nakano, Yoko Ikeda, Takazumi Taniguchi, Tomohito Yagi, Masahiro Fuwa, Natsue Omi, Yuichi Tokuda, Masami Tanaka, Kengo Yoshii, Masaaki Kageyama, Shigeta Naruse, Akira Matsuda, Kazuhiko Mori, Shigeru Kinoshita, Kei Tashiro   +14 more
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source