Results 301 to 310 of about 1,051,148 (367)

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Genome-wide association study of plasma amino acids and Mendelian randomization for cardiometabolic traits. [PDF]

Sci Rep
Toki R, Fushiki S, Kojima S, Sutoh Y, Otsuka-Yamasaki Y, Harada S, Iida M, Hirata A, Miyagawa N, Matsumoto M, Edagawa S, Miyake A, Kuwabara K, Hirayama A, Sugimoto M, Sato A, Amano K, Soga T, Tomita M, Arakawa K, Kinoshita K, Sakurai-Yageta M, Tamiya G, Ohmomo H, Shimizu A, Okamura T, Takebayashi T.   +26 more
europepmc   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Identification of key genes associated with mesocotyl length through a genome-wide association study in rice. [PDF]

Front Plant Sci
Xue L, Wang S, Zhang Q, Han B, Cui D, Han L, Deng J, Ma X.   +7 more
europepmc   +1 more source

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Chromosome 21 variants tied to severe asthma exacerbations: A genome-wide association study in a Brazilian population. [PDF]

J Allergy Clin Immunol Glob
de Santana MBR, Cruz ÁA, Teixeira HMP, Silva HDS, Abdel-Aziz MI, Hashimoto S, Vijverberg SJH, Herrera-Luis E, Pino-Yanes M, Burchard EG, Chung KF, Djukanovic R, Dahlén SE, Adcock IM, Cox C, Brunetti T, Campbell M, Rafaels N, Barnes KC, Maitland-van der Zee AH, Figueiredo CA, Costa RS.   +21 more
europepmc   +1 more source

Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study

, 2008
Yao-Zhong Liu, Scott G. Wilson, Liang Wang, Xiaogang Liu, Yan-Fang Guo, Jian Li, Han Yan, Panos Deloukas, Nicole Soranzo, Usha Chinnapen-Horsley, Alesandra Cervino, Frances M. K. Williams, Dong-Hai Xiong, Yin-Ping Zhang, Tian-Bo Jin, Shawn Levy, Christopher J. Papasian, Betty M. Drees, James J. Hamilton, Robert R. Recker, Tim D. Spector, Hong‐Wen Deng   +21 more
openalex   +2 more sources

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum. [PDF]

Front Genet
Umar AB, Ramalingam AP, Sadia B, Awan FS, Khan FA, Nasir M, Bernardo A, St Amand P, Bai G, Prasad PVV, Perumal R.   +10 more
europepmc   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

Advanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao, Qianqian Bai, Yifei Zhao, Xingyi Dai, Yuan Liu, Xiao Han, Jianhua Hao   +6 more
wiley   +1 more source