Results 321 to 330 of about 1,051,148 (367)

Genome-wide association study of post COVID-19 syndrome in a population-based cohort in Germany. [PDF]

Sci Rep
Ruß AK, Schreiber S, Lieb W, Vehreschild JJ, Heuschmann PU, Illig T, Appel KS, Vehreschild MJGT, Krefting D, Reinke L, Viebke A, Poick S, Störk S, Reese JP, Zoller T, Krist L, Ellinghaus D, Foesel BU, Gieger C, Lorenz-Depiereux B, Witzenrath M, Anton G, Krawczak M, Heyckendorf J, Bahmer T.   +24 more
europepmc   +1 more source

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

Advanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang, Mengyuan Qian, Yirui Shi, Jiaxu Cao, Min Xu, Xin Wen, Yunxia Yan, Sha Liu, Hongwei Chen, Shanshan Liu, Jun Yang, Lingyun Sun   +11 more
wiley   +1 more source

Cross-ancestry genome-wide association study identifies new susceptibility genes for preeclampsia. [PDF]

BMC Pregnancy Childbirth
Shan Y, Hu H, Chu Y.
europepmc   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source

Genome-wide association study of susceptibility to acute respiratory distress syndrome

Guillen-Guio B, Suarez-Pajes E, Tosco-Herrera E, Hernandez-Beeftink T, Lorenzo-Salazar JM, Chang D, González-Montelongo R, Rubio-Rodríguez LA, Leavy OC, Allen RJ, Corrales A, Cruz R, Bardají-Carrillo M, Carracedo A, Tamayo E, Kerchberger VE, Ware LB, Yaspan BL, Scholz M, Scherag A, Villar J, Wain LV, Flores C.   +22 more
europepmc   +1 more source

Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese. [PDF]

Poult Sci
Zhao X, Mei Z, Li H, Wu Y, Pan L, Cao Y.
europepmc   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

Genome wide association study reveals novel associations with face morphology. [PDF]

PLoS One
Alshehhi A, Mousa M, Tay GK, Werghi N, AlSafar H.   +4 more
europepmc   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

Genome-Wide Association Study for Weight-Related Traits in <i>Scylla paramamosain</i> Using Whole-Genome Resequencing. [PDF]

Animals (Basel)
Chen L, Zhang Y, Jia P, Zhou S, Qin Q, Zhang W, Huang K, Wang X, Ye H.   +8 more
europepmc   +1 more source