Results 81 to 90 of about 3,563,004 (328)

u-Genome: A Database on Genome Design in Unicellular Genomes

open access: yesIn Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2005
Unicellular eukaryotes were among the first ones to be selected for complete genome sequencing because of the small size of their genomes and their interactions with humans and a broad range of animals and plants. Currently, ten completely sequenced unicellular genome sequences have been publicly released and as the number of available unicellular ...
Sakharkar, K.R.   +5 more
openaire   +2 more sources

GENOME TREES AND THE NATURE OF GENOME EVOLUTION [PDF]

open access: yesAnnual Review of Microbiology, 2005
Genome trees are a means to capture the overwhelming amount of phylogenetic information that is present in genomes. Different formalisms have been introduced to reconstruct genome trees on the basis of various aspects of the genome. On the basis of these aspects, we separate genome trees into five classes: (a) alignment-free trees based on statistic ...
Snel, B., Huynen, M.A., Dutilh, B.E.
openaire   +4 more sources

A Phylogenomic Supertree of Birds

open access: yesDiversity, 2019
It has long been appreciated that analyses of genomic data (e.g., whole genome sequencing or sequence capture) have the potential to reveal the tree of life, but it remains challenging to move from sequence data to a clear understanding of evolutionary ...
Rebecca T. Kimball   +13 more
doaj   +1 more source

Multipartite viruses: A decentralized mode of functioning. [O.24] [PDF]

open access: yes, 2015
Multipartite viruses are characterized by a genome composed of two or more nucleic acid segments, each encapsidated indivually. A classical view in virology assumes that the viral replication cycle occurs within individual cells, where the whole viral ...
Blanc, Stéphane   +4 more
core  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Visualization for genomics: the Microbial Genome Viewer [PDF]

open access: yesBioinformatics, 2004
Abstract Summary: A Web-based visualization tool, the Microbial Genome Viewer, is presented that allows the user to combine complex genomic data in a highly interactive way. This Web tool enables the interactive generation of chromosome wheels and linear genome maps from genome annotation data stored in a MySQL database.
Kerkhoven, R.   +4 more
openaire   +4 more sources

Biosynthesis of Akaeolide and Lorneic Acids and Annotation of Type I Polyketide Synthase Gene Clusters in the Genome of Streptomyces sp. NPS554

open access: yesMarine Drugs, 2015
The incorporation pattern of biosynthetic precursors into two structurally unique polyketides, akaeolide and lorneic acid A, was elucidated by feeding experiments with 13C-labeled precursors.
Tao Zhou   +5 more
doaj   +1 more source

Comprehensive genomic characterization defines human glioblastoma genes and core pathways. [PDF]

open access: yes, 2008
Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
Cancer Genome Atlas Research Network
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The Ectocarpus Genome and Brown Algal Genomics

open access: yes, 2012
Brown algae are important organisms both because of their key ecological roles in coastal ecosystems and because of the remarkable biological features that they have acquired during their unusual evolutionary history. The recent sequencing of the complete genome of the filamentous brown alga Ectocarpus has provided unprecedented access to the molecular
Colin Brownlee   +118 more
openaire   +4 more sources

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