Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi+11 more
wiley +1 more source
Expanding kinetoplastid genome annotation through protein structure comparison. [PDF]
Trinidad-Barnech JM+3 more
europepmc +1 more source
Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster [PDF]
Casey Bergman, Joe Carlson, S Celniker
openalex +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
Mitochondrial genome annotation with MFannot: a critical analysis of gene identification and gene model prediction. [PDF]
Lang BF+5 more
europepmc +1 more source
Pseudomonas aeruginosa Genome Database and PseudoCAP: facilitating community-based, continually updated, genome annotation [PDF]
Geoffrey L. Winsor+8 more
openalex +1 more source
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
High-Performance Genome Annotation for a Safer and Faster-Developing Phage Therapy. [PDF]
Culot A, Abriat G, Furlong KP.
europepmc +1 more source
PhaGAA: an integrated web server platform for phage genome annotation and analysis. [PDF]
Wu J+8 more
europepmc +1 more source
The Vertebrate Genome Annotation (Vega) database [PDF]
Jennifer Ashurst
openalex +1 more source