Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Generation and analysis of a mouse multitissue genome annotation atlas. [PDF]
Genome ResAdams M, Vollmers C.
europepmc +1 more source
Update on genome completion and annotations: Protein Information Resource [PDF]
, 2004 Cathy Wu, Daniel W. Nebert
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche +16 more
wiley +1 more source
Regulatory genome annotation of 33 insect species. [PDF]
ElifeAsma H +7 more
europepmc +1 more source
Genofunc: genome annotation and identification of genome features for automated pipelining analysis of virus whole genome sequences. [PDF]
BMC Bioinformatics, 2023 Yu X.
europepmc +1 more source
Genome annotation by high-throughput 5′ RNA end determination [PDF]
, 2004 Byung Joon Hwang +2 more
openalex +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
The rice genome annotation project: an updated database for mining the rice genome. [PDF]
Nucleic Acids ResHamilton JP, Li C, Buell CR.
europepmc +1 more source
Chloroplast Genome Annotation Tools: Prolegomena to the Identification of Inverted Repeats. [PDF]
Int J Mol Sci, 2022 Turudić A +5 more
europepmc +1 more source