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Comparative Genome Annotation

2017
Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König   +2 more
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Genome annotation

Plant Physiology and Biochemistry, 2001
85 ref.
Aubourg, Sebastien, Rouzé, Pierre
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Bacterial Genome Annotation

2012
Annotation of prokaryotic sequences can be separated into structural and functional annotation. Structural annotation is dependent on algorithmic interrogation of experimental evidence to discover the physical characteristics of a gene. This is done in an effort to construct accurate gene models, so understanding function or evolution of genes among ...
Nicholas, Beckloff   +3 more
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Towards multidimensional genome annotation

Nature Reviews Genetics, 2006
Our information about the gene content of organisms continues to grow as more genomes are sequenced and gene products are characterized. Sequence-based annotation efforts have led to a list of cellular components, which can be thought of as a one-dimensional annotation.
Jennifer L, Reed   +3 more
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Comparative Genome Annotation

Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. A large proportion of such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, Nachtweide   +2 more
openaire   +2 more sources

Plant Genome Annotation Methods

2009
Annotation of plant genomic sequences can be separated into structural and functional annotation. Structural annotation is the foundation of all genomics as without accurate gene models understanding gene function or evolution of genes across taxa can be impeded.
Shu, Ouyang   +4 more
openaire   +2 more sources

Annotation of Parasite Genomes

2004
Genome annotation is the application of useful biological descriptions to sequence data. Different levels of time and effort can be invested to produce correspondingly different depths of annotation depending on what methods are employed. Researchers using genome data should, therefore, understand how annotations are generated to assess their validity ...
Matthew, Berriman, Midori, Harris
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Annotating the Regulatory Genome

2010
Determining the timing and molecular repertoire responsible for gene expression is fundamental to understanding a gene's function. Heritable differences in this character are increasingly regarded as explanatory for complex and common traits. For many known trait-predisposing genes, studies have sought to elucidate the associated logic behind gene ...
Stephen B, Montgomery   +3 more
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Genome Sequencing and Annotation

2003
The availability of complete microbial genome sequences enormously facilitates experimental molecular investigations of the respective organisms by providing complete lists of genes, their genetic contexts, and their predicted functions. This can be used in a number of ways to focus studies on bacterial pathogenesis and also vaccine development (1,2 ...
A C, Jeffries, N J, Saunders, D W, Hood
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An Introduction to Genome Annotation

Current Protocols in Bioinformatics, 2015
AbstractGenome projects have evolved from large international undertakings to tractable endeavors for a single lab. Accurate genome annotation is critical for successful genomic, genetic, and molecular biology experiments. These annotations can be generated using a number of approaches and available software tools.
Michael S, Campbell, Mark, Yandell
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