Results 331 to 340 of about 2,597,991 (390)

Chromosome-level genome assembly and annotation of the kuruma shrimp Marsupenaeus japonicus. [PDF]

Sci Data
Wei Y, Xu H, Zhou Z, Wang P, Cheng W, Huang H, Ding S, Mao Y.   +7 more
europepmc   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Chromosome level genome assembly of tea tussock moth, Euproctis pseudoconspersa. [PDF]

Sci Data
Zhang K, Long Y, Qu H, Wang L, Li M, Luo Z, Cai X, Bian L, Fu N, Chen L, Liu N, Xiu C, Li Z.   +12 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Near complete T2T genome assembly of the banded goonch (Bagarius rutilus). [PDF]

Sci Data
Liu Y, Zhu F, Lei C, Yang H, Li Y, Li J, Liu M, Chen W.   +7 more
europepmc   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

A High-quality chromosome-level genome assembly of Swertia przewalskii Pissjauk. [PDF]

Sci Data
Shuang H, Niu Y, Xu H, Yu J, Han Y, Zheng Q, Guan R, Zhang F, Chen S.   +8 more
europepmc   +1 more source

Chromosome-level genome assembly of the predatory stink bug, Eocanthecona furcellata (Wolff). [PDF]

Sci Data
Hu QL, Zhuo JC, Zhang CX.
europepmc   +1 more source

Chromosome-level genome assembly and annotation of the endangered plant Primula kwangtungensis (Primulaceae). [PDF]

Sci Data
Liu T, Xiao Y, Wu X, Chen S, Chen S, Mayrose I, Hao G, Wang R, Xu Y.   +8 more
europepmc   +1 more source

A chromosome-level genome assembly of the flat mite Brevipalpus obovatus. [PDF]

Sci Data
He HD, Liang L, Jin DC, Yi TC.
europepmc   +1 more source