Results 341 to 350 of about 2,597,991 (390)

The telomere-to-telomere genome assembly of the Triplophysa erythraea (Nemacheilidae hypogean fishes). [PDF]

open access: yesSci Data
Wang C   +11 more
europepmc   +1 more source

Genome Assembly

Methods in Molecular Biology
A. Kalyanaraman
semanticscholar   +2 more sources

Assembling vertebrate genomes

Nature Reviews Genetics, 2021
The Vertebrate Genomes Project, which aims to produce high-quality reference genomes for all 71,657 living and named vertebrate species, reports the generation of high-quality genome assemblies for the first 16 species and describes the biological findings that these genomes have informed.
openaire   +2 more sources

Phased Genome Assemblies

2022
The ultimate goal of de novo assembly of reads sequenced from a diploid individual is the separate reconstruction of the sequences corresponding to the two copies of each chromosome. Unfortunately, the allele linkage information needed to perform phased genome assemblies has been difficult to generate.
openaire   +2 more sources

Sesame Genome Assembly

2021
Genome assembly strategy is a crucial step for reconstructing high-quality genomes in any genome project. With the continuous innovation of new sequencing platforms, various methods of genome assembly have been developed and applied in genome assembly.
Hongmei Miao   +3 more
openaire   +1 more source

Genome Sequencing and Assembly

2011
Decoding the genome sequence is becoming a fundamental tool for molecular, genetic, and genomic studies. This chapter reviews the history of DNA sequencing and technical principles of different sequencing platforms, and compares the strengths and weaknesses of different techniques for high-throughput genome sequencing applications are compared. It also
Manfred G, Grabherr   +2 more
openaire   +2 more sources

Democratizing long-read genome assembly

Cell Systems, 2021
De novo assembled genomes serve as the backbone for modern genomics. In an article in this issue of Cell Systems, Ekim et al. present the mdBG assembler that can assemble genomes 100-fold faster than previous methods, including a human genome in under 10 min, which unlocks pan-genomics for many species.
Melanie, Kirsche, Michael C, Schatz
openaire   +2 more sources

Genome Assembly

2018
Genome assembly uses sequence similarity to go from sequencing reads to longer contiguous sequences (contigs). Scaffolds are contigs linked together by gaps where the order and orientation of the contigs is known but the exact sequence connecting two contigs is unknown, represented by Ns which estimate the gap length.
openaire   +2 more sources

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