Results 361 to 370 of about 1,963,187 (422)

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

Advanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie, Shang‐Hui Ye, Yu‐Ting Yue, Bao‐Hong Shi, Jing‐Ping Xu, Lian‐Jie Li, Zheng‐Biao Zou, Matthew B. Greenblatt, Na Li, Xian‐Wen Yang, Ren Xu   +10 more
wiley   +1 more source

CRISPR/Cas9 Genome Editing in the Diamondback Moth: Current Progress, Challenges, and Prospects. [PDF]

Int J Mol Sci
Asad M, Chang Y, Liao J, Yang G.
europepmc   +1 more source

Cyanobacterial type I CRISPR-Cas systems: distribution, mechanisms, and genome editing applications. [PDF]

Front Bioeng Biotechnol
Zhang Y, Yang S, Zheng X, Tan X.
europepmc   +1 more source

Enhanced Genome Editing Activity with Novel Chimeric ScCas9 Variants in Rice. [PDF]

Adv Sci (Weinh)
Liang Z, Wu Y, Deng S, Wei S, Zhang K, Guo Y.   +5 more
europepmc   +1 more source

Efficient genome editing in dicot plants using calreticulin promoter-driven CRISPR/Cas system. [PDF]

Mol Hortic
Li B, Shang Y, Wang L, Lv J, Wu Q, Wang F, Chao J, Mao J, Ding A, Wu X, Xue K, Chen C, Cui M, Sun Y, Zhang H, Dai C.   +15 more
europepmc   +1 more source

Characterization of the genome editing with miniature DNA nucleases TnpB and IscB in Escherichia coli strains. [PDF]

Commun Biol
Tang H, Gao J, Wang H, Sun M, Zhang S, Song C, Li Q.   +6 more
europepmc   +1 more source

Saturation genome editing ofRNU4-2reveals distinct dominant and recessive neurodevelopmental disorders

De Jonghe J, Kim HC, Adedeji A, Leitão E, Dawes R, Chen Y, Blakes AJ, Simons C, Rius R, Alvi JR, Amblard F, Austin-Tse C, Baer S, Balton EV, Blanc P, Calame DG, Coutton C, Cunningham CA, Dargie N, Dipple KM, Du H, El Chehadeh S, Glass I, Gleeson JG, Grunewald O, Gueguen P, Harbuz R, Jacquemont M, Leventer RJ, Marijon P, Messaoud O, Sultan T, Thauvin C, Vincent-Delorme C, Yilmaz Gulec E, Thevenon J, Mendez R, MacArthur DG, Depienne C, Nava C, Whiffin N, Findlay GM.   +41 more
europepmc   +1 more source

Application of a GRF-GIF chimera enhances plant regeneration for genome editing in tomato

Swinnen G, Lizé E, Sánchez ML, Stolz S, Soyk S.   +4 more
europepmc   +1 more source

Search-and-replace genome editing without double-strand breaks or donor DNA

Nature, 2019
Most genetic variants that contribute to disease1 are challenging to correct efficiently and without excess byproducts2–5. Here we describe prime editing, a versatile and precise genome editing method that directly writes new genetic information into a ...
Aditya Raguram, Christopher Wilson, David R Liu   +2 more
exaly   +2 more sources