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2022
The diabetes types and its complications have varying developmental and metabolic pathways. There is an interplay of nongenetic and genetic components in pathogenesis of diabetes and its complications. There are several established genes such as ABCC8, TCF7L2, SLC2A2, and CAPN10 which are known to influence blood insulin and glucose levels.
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The diabetes types and its complications have varying developmental and metabolic pathways. There is an interplay of nongenetic and genetic components in pathogenesis of diabetes and its complications. There are several established genes such as ABCC8, TCF7L2, SLC2A2, and CAPN10 which are known to influence blood insulin and glucose levels.
openaire +2 more sources
2021
Although barley is of great importance for the brewing and animal feed industries and is regarded as a model for small grain cereals, only a few results on targeted gene modification using CRISPR/Cas endonuclease technology have been published to date.
Martin Becker, Goetz Hensel
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Although barley is of great importance for the brewing and animal feed industries and is regarded as a model for small grain cereals, only a few results on targeted gene modification using CRISPR/Cas endonuclease technology have been published to date.
Martin Becker, Goetz Hensel
openaire +1 more source
Genome editing of a rice CDP-DAG synthase confers multipathogen resistance
Nature, 2023Gan Sha +31 more
semanticscholar +1 more source
Boosting plant genome editing with a versatile CRISPR-Combo system
Nature Plants, 2022Changtian Pan +8 more
semanticscholar +1 more source
Structural biology of CRISPR–Cas immunity and genome editing enzymes
Nature Reviews Microbiology, 2022Joy Y. Wang, P. Pausch, J. Doudna
semanticscholar +1 more source
Regulate genome-edited products, not genome editing itself
Nature Biotechnology, 2016Dana Carroll +4 more
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Precise plant genome editing using base editors and prime editors
Nature Plants, 2021K. Molla +3 more
semanticscholar +1 more source
Programmed genome editing by a miniature CRISPR-Cas12f nuclease
Nature Chemical Biology, 2021Zhaowei Wu +10 more
semanticscholar +1 more source
PAM-less plant genome editing using a CRISPR–SpRY toolbox
Nature Plants, 2021Qiurong Ren +19 more
semanticscholar +1 more source
2017
Caenorhabditis elegans, a 1 mm long free-living nematode, is a traditional model animal for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies include its rapid life cycle, well-annotated genome, simple morphology, and transparency.
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Caenorhabditis elegans, a 1 mm long free-living nematode, is a traditional model animal for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies include its rapid life cycle, well-annotated genome, simple morphology, and transparency.
openaire +4 more sources