Results 171 to 180 of about 743,811 (309)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The Karnataka Individual Genome Project expands the human reference landscape to include South Asia. [PDF]

open access: yesHGG Adv
Ganesh A   +9 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Moroccan genome project: genomic insight into a North African population. [PDF]

open access: yesCommun Biol
El Fahime E   +7 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

THE HUMAN GENOME PROJECT: LEGAL ASPECTS, VOLUME III

open access: yes, 1994
Human genome and insurance law -- Presentations -- Genetic information and access to health insurance / Thomas H. Murray -- Insurance and genetics: a purposive analysis / Alexander Morgan Capron -- The genetic code and insurance contracts / Aurelio ...

core  

The Ecological Genome Project and the Promises of Ecogenomics for Society: Realising a Shared Vision as One Health. [PDF]

open access: yesBioethics
Capps B   +13 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

The peruvian genome project: expanding the global pool of genome diversity from South America. [PDF]

open access: yesFront Genet
Guio H   +22 more
europepmc   +1 more source

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