Results 11 to 20 of about 4,549,742 (256)
The Sequence of the Human Genome [PDF]
Science, 2001 A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage of the genome) from both ends of plasmid clones made from the DNA of ...
Eugene W Myers +2 more
exaly +8 more sources
Genome Sequence of Canine Herpesvirus. [PDF]
PLoS ONE, 2016 Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United ...
Konstantinos V Papageorgiou +5 more
doaj +4 more sources
Practical Neurology, 2021 The costs of whole-genome sequencing have rapidly decreased, and it is being increasingly deployed in large-scale clinical research projects and introduced into routine clinical care. This will lead to rapid diagnoses for patients with genetic disease but also introduces uncertainty because of the diversity of human genomes and the potential ...
Huw R Morris, Henry Houlden, James Polke
openaire +4 more sources
Proceedings of the National Academy of Sciences, 1984 Unique DNA sequences can be determined directly from mouse genomic DNA. A denaturing gel separates by size mixtures of unlabeled DNA fragments from complete restriction and partial chemical cleavages of the entire genome. These lanes of DNA are transferred and UV-crosslinked to nylon membranes.
Church, George, Gilbert, Walter
openaire +4 more sources
Sequencing technologies and genome sequencing [PDF]
Journal of Applied Genetics, 2011 The high-throughput - next generation sequencing (HT-NGS) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the Sanger method.
Pareek, Chandra Shekhar +2 more
openaire +4 more sources
Of Mice and Genome Sequence [PDF]
Cell, 2001 Availability of the mouse genome sequence will have a major impact on the study of vertebrate evolution, mammalian biology, and animal models of human disease. Resources to explore genome biology in mice will maximize the effect of this watershed event.
Hamilton, B A, Frankel, W N
openaire +3 more sources
The complete chloroplast genome and phylogenetic analysis of Manglietia ventii (Magnoliaceae)
Mitochondrial DNA. Part B. Resources, 2022 Manglietia ventii is a highly ornamental timber tree species that is listed as endangered on the IUCN Red List. This study was conducted on the complete chloroplast genome of M. ventii.
Yuchang Wang, Dawei Wang
doaj +1 more source
GSAlign: an efficient sequence alignment tool for intra-species genomes
BMC Genomics, 2020 Background Personal genomics and comparative genomics are becoming more important in clinical practice and genome research. Both fields require sequence alignment to discover sequence conservation and variation.
Hsin-Nan Lin, Wen-Lian Hsu
doaj +1 more source
Sequencing the Human Genome [PDF]
Science, 1986 The title of the report by R. Myerowitz and N. Hogikyan on page 1646 of the issue of 27 June was incorrect. It should have been "Different mutations in Ashkenazi Jews and non-Jewish French Canadians with Tay-Sachs disease."
James Bruce Walsh, Jon Marks
openaire +6 more sources
Mitochondrial DNA. Part B. Resources, 2023 Solanum iopetalum belongs to the Solanaceae family and is one of the tuber-bearing wild Solanum species. In this study, chloroplast genome sequencing of the species, completed with Illumina sequencing technology, is presented.
Tae-Ho Park
doaj +1 more source