Results 221 to 230 of about 733,963 (352)

Mechanisms Of Genome Stability In The Hyperthermophilic Archaeon Sulfolobus acidocaldarius

, 2011
Cynthia J. Sakofsky
openalex   +1 more source

Supplementary Figures 1-3 from Tpx2 Controls Spindle Integrity, Genome Stability, and Tumor Development

, 2023
Cristina Aguirre‐Portolés, Alexander W. Bird, Anthony A. Hyman, Marta Cañamero, Ignacio Pérez de Castro, Marcos Malumbres   +5 more
openalex   +1 more source

RB dependent transcriptional regulation at mitotic centromeres preserves genome stability. [PDF]

Life Sci Alliance
Crowley EA, Manning AL.
europepmc   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

The Role of Mitochondrial Genome Stability and Metabolic Plasticity in Thyroid Cancer. [PDF]

Biomedicines
Ren L, Liu W, Zheng J, Wu Q, Ai Z.
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase

, 1999
Yuanhong Wang, Gerald S. Shadel
openalex   +1 more source

A SETD2-CDK1-lamin axis maintains nuclear morphology and genome stability. [PDF]

Nat Cell Biol
Khan A, Zhang C, Nguyen PG, Metts JM, Collins LC, Jain K, Mills CA, Vlach L, Li K, Brademeyer AL, Bowman BM, Major MB, Aubé J, Herring LE, Rathmell WK, Mason FM, Davis IJ, Zhang Q, Strahl BD.   +18 more
europepmc   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Vertebrate WRNIP1 and BLM are required for efficient maintenance of genome stability

, 2008
Tomoko Hayashi, Masayuki Seki, Eri Inoue, Akari Yoshimura, Yumiko Kusa, Shusuke Tada, Takemi Enomoto   +6 more
openalex   +2 more sources