Results 181 to 190 of about 714,798 (302)

Rethinking Parkinson's disease genetics in the precision medicine era: why genomic diversity matters? [PDF]

Front Genet
Pinheiro Gusmão CT, Scaini G, Ferreira de Souza E, Vicente Lacerda RA, Costa MA, Mehanna R, Quevedo J, Ribeiro Junior HL.   +7 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

From Fermentation to Function: Genomic Diversity and Probiotic Potential in the Reclassified <i>Lactobacillus</i> Lineage. [PDF]

Comput Struct Biotechnol J
Chaichana N, Singkhamanan K, Wonglapsuwan M, Chusri S, Pomwised R, Surachat K.   +5 more
europepmc   +1 more source

A Lightweight Procedural Layer for Hybrid Experimental–Computational Workflows in Materials Science

Advanced Engineering Materials, EarlyView.
We unveil a prototype hybrid‐workflow framework that fuses automatedcomputation with hands‐on experiments. Built atop pyiron, a lightweight, parameterized layer translates procedure descriptions into executable manual steps, syncing instrument settings, human interventions, and data capture in real‐time today.
Steffen Brinckmann, Sarath Menon, Raphael Röske, Johannes Steinhülb, Michael Selzer, Jan Janssen, Tilmann Hickel, Ruth Schwaiger, Jörg Neugebauer   +8 more
wiley   +1 more source

Genomic diversity in the critical priority pathogen Klebsiella pneumoniae: global and regional perspectives. [PDF]

BMC Microbiol
Kapoor A, Dey T, Kale TM, Kumar A, Tak V, Nag VL, Shankar M.   +6 more
europepmc   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Continent-wide view of genomic diversity and divergence in the wolves of Asia. [PDF]

Commun Biol
Hennelly LM, Parreira BR, Noble A, Scharff-Olsen CH, Aytekin MÇK, Şekercioğlu ÇH, Kosintsev P, Paule L, Hulva P, Stenøien HK, Habib B, Fatima H, Sarwar G, El-Haddad SP, Youssef A, Hailer F, Sun X, Martins NFG, Gilbert MTP, Sacks BN, Sinding MS, Gopalakrishnan S.   +21 more
europepmc   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source

Genomic diversity and surveillance of SARS-CoV-2 in Nigeria. [PDF]

BMC Genomics
Kono TJY, Onyemata EJ, Blanco N, Onwuamah CK, Ndodo N, Oluniyi P, Lawal O, Riley C, Osawe S, Baxter C, Winters A, Xiong C, Happi CT, Salako BL, Adetifa I, Abimiku A, Charurat M, Stafford KA, INFORM Africa Research Study Group.   +18 more
europepmc   +1 more source

Structure Formation in Butterfly Scales: Interplay of Genetic Control, Mechanical Instabilities, and Dynamic Material Properties

Advanced Functional Materials, EarlyView.
Butterfly wing scales are intricate cuticular functional nanosctructures. This perspective suggests that spatially varying material properties, cytoskeletal constraints, and growth‐driven mechanical instabilities shape the resulting nanoscale architectures created from single cells.
Anupama Prakash, Victoria Lloyd, Yi Yang, Anna‐Lee Jessop, Anthony McDougal, Primož Pirih, Guillaume Duclos, Andrew Parnell, Mathias Kolle, Nicola J. Nadeau, Bodo D. Wilts   +10 more
wiley   +1 more source