Results 151 to 160 of about 1,136,601 (292)

Fluorescence-Based Detection of <i>KRAS</i> Mutations in Genomic DNA Using Magnetic Bead-Coupled LDR Assay. [PDF]

Methods Protoc
Morimoto C, Hashimoto M.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

7C31 How is a long strand of genomic DNA organized in the cell?

, 2012
Kazuhiro Maeshima, Hideaki Takata
openalex   +2 more sources

Development of a Genomic DNA Reference Material Panel for Rett Syndrome (MECP2-Related Disorders) Genetic Testing [PDF]

, 2014
Lisa V. Kalman, Jack Tarleton, Alan K. Percy, Swaroop Aradhya, Sherri J. Bale, Shannon Barker, Pınar Bayrak‐Toydemir, Christina Bridges, Arlene Buller‐Burckle, Soma Das, Ramaswamy K. Iyer, Timothy D. Vo, Val Zvereff, Lorraine H. Toji   +13 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Endogenous p21 levels protect genomic stability by suppressing both excess and restrained nascent DNA syntheses

Nicolás Luis Calzetta, Sabrina F. Mansilla, Candelaria Mares Ahlers, Agostina P. Bertolin, Lilen Ivonne Caimi, Sofía Venerus Arbilla, Jingkun Zeng, Lisa Wiesmüller, Vanesa Gottifredi   +8 more
openalex   +1 more source

SPECTRAL ANALYSIS OF GUANINE AND CYTOSINE FLUCTUATIONS OF MOUSE GENOMIC DNA [PDF]

, 2004
WENTIAN LI, DIRK HOLSTE
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Author Correction: RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells. [PDF]

Commun Biol
Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.   +20 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source