Results 11 to 20 of about 4,131,506 (305)
An investigation into inter- and intragenomic variations of graphic genomic signatures [PDF]
arXiv, 2015 We provide, on an extensive dataset and using several different distances, confirmation of the hypothesis that CGR patterns are preserved along a genomic DNA sequence, and are different for DNA sequences originating from genomes of different species.
Karamichalis, Rallis +3 more
arxiv +6 more sources
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA [PDF]
Biology Open, 2012 Summary Topoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5′-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions ...
Ka C Lee +10 more
semanticscholar +5 more sources
Reconsidering the significance of genomic word frequency [PDF]
arXiv, 2006 We propose that the distribution of DNA words in genomic sequences can be primarily characterized by a double Pareto-lognormal distribution, which explains lognormal and power-law features found across all known genomes. Such a distribution may be the result of completely random sequence evolution by duplication processes.
Csűrös, Miklós +2 more
arxiv +6 more sources
Genomic DNA in human blastocoele fluid
Reproductive BioMedicine Online, 2013 IVF often requires embryo cryopreservation through vitrification. During the vitrification process, the embryos can be collapsed by withdrawing the blastocoele fluid. The metabolomic profile of blastocoele fluid has been recently investigated by high-performance liquid chromatography-electrospray ionization-mass spectrometry to provide metabolite ...
BULLETTI, CARLO +6 more
openaire +6 more sources
Proceedings of the National Academy of Sciences of the United States of America, 1992 Marianne Frommer +7 more
openalex +2 more sources
The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. [PDF]
, 2016 Despite decades of work, our understanding of the distribution of fitness effects of segregating genetic variants in natural populations remains largely incomplete. One form of selection that can maintain genetic variation is spatially varying selection,
Begun, David J +3 more
core +12 more sources
Preparation of enteroinvasive Escherichia coli reference materials for food analysis
Zhongguo shipin weisheng zazhi, 2021 ObjectiveTo satisfy the demands of laboratory quality control and proficiency testing for the detection of enteroinvasive Escherichia coli (EIEC), a stable EIEC reference material was developed with independent intellectual property rights, good ...
ZHAO Linna +4 more
doaj +1 more source
Preliminary study of familial nonsyndromic tooth agenesis caused by ectodysplasin A mutation
口腔疾病防治, 2023 Objective To explore the pathogenic genes in a Chinese family affected by nonsyndromic tooth agenesis so as to study the pathogenesis of oligodontia. Methods Hospital ethical approval and informed consent of the patients and family members were obtained.
WANG Huihui +4 more
doaj +1 more source
Molecular Genetics & Genomic Medicine, 2020 Background Lipopolysaccharide‐responsive and beige‐like anchor (LRBA) deficiency is a rare autosomal recessive common variable immunodeficiency (CVID), affecting 1:25,000–1:50,000 people worldwide.
Anh N. L. Phan +7 more
doaj +1 more source
Metal-Binding Antimicrobial Peptide SIF4 Kills Escherichia coli by Targeting Cytoplasmic Biomacromolecules without Cytoplasmic Membrane Damage: A Mechanistic Study [PDF]
Shipin Kexue, 2023 To explore how metal-binding antimicrobial peptide SIF4 kills foodborne Escherichia coli by targeting nucleic acid and protein in the cytoplasmic membrane without cytoplasmic membrane damage, the effect of SIF4 on intracellular nucleic acid biosynthesis ...
LI Yuzhen, XIAO Huaiqiu, LIU Miao, WANG Lin, ZENG Mengqi, ZHAO Mouming
doaj +1 more source