Results 11 to 20 of about 1,062,471 (320)

Preparation of enteroinvasive Escherichia coli reference materials for food analysis

Zhongguo shipin weisheng zazhi, 2021
ObjectiveTo satisfy the demands of laboratory quality control and proficiency testing for the detection of enteroinvasive Escherichia coli (EIEC), a stable EIEC reference material was developed with independent intellectual property rights, good ...
ZHAO Linna, WANG Xueshuo, LIU Na, CUI Shenghui, LU Yong   +4 more
doaj   +1 more source

Preliminary study of familial nonsyndromic tooth agenesis caused by ectodysplasin A mutation

口腔疾病防治, 2023
Objective To explore the pathogenic genes in a Chinese family affected by nonsyndromic tooth agenesis so as to study the pathogenesis of oligodontia. Methods Hospital ethical approval and informed consent of the patients and family members were obtained.
WANG Huihui, WU Qing , XU Bin, LING Qi , WU Yiqun   +4 more
doaj   +1 more source

Novel compound heterozygous stop‐gain mutations of LRBA in a Vietnamese patient with Common Variable Immune Deficiency

Molecular Genetics & Genomic Medicine, 2020
Background Lipopolysaccharide‐responsive and beige‐like anchor (LRBA) deficiency is a rare autosomal recessive common variable immunodeficiency (CVID), affecting 1:25,000–1:50,000 people worldwide.
Anh N. L. Phan, Thuy T. T. Pham, Nghia Huynh, Tuan M. Nguyen, Cuc T. T. Cao, Duong T. Nguyen, Duc T. Le, Chi‐Bao Bui   +7 more
doaj   +1 more source

Metal-Binding Antimicrobial Peptide SIF4 Kills Escherichia coli by Targeting Cytoplasmic Biomacromolecules without Cytoplasmic Membrane Damage: A Mechanistic Study [PDF]

Shipin Kexue, 2023
To explore how metal-binding antimicrobial peptide SIF4 kills foodborne Escherichia coli by targeting nucleic acid and protein in the cytoplasmic membrane without cytoplasmic membrane damage, the effect of SIF4 on intracellular nucleic acid biosynthesis ...
LI Yuzhen, XIAO Huaiqiu, LIU Miao, WANG Lin, ZENG Mengqi, ZHAO Mouming
doaj   +1 more source

The complete mitochondrial genome of Cepola schlegelii from the East China Sea

Mitochondrial DNA. Part B. Resources, 2022
Cepola schlegelii (Bleeker 1854) belongs to the genus Cepola in the family Cepolidae and order Priacanthiformes. The complete mitochondrial genome of C. schlegelii was sequenced and analyzed by a high-throughput sequencing approach.
Panjiao Liang, Shouqiang Wang, Ye Lin, Li Wang, Linlin Zhao, Shenghao Liu   +5 more
doaj   +1 more source

Not seeing the genomes for the DNA [PDF]

Briefings in Functional Genomics, 2012
This Short Communication highlights the diversity of 'secondary' genome data (like mitochondrial and plastid genomes) that can be gleaned from next-generation sequencing projects, and encourages researchers to be mindful that these data are often as informative and useful as the 'primary' genome data.
openaire   +3 more sources

MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability

eLife, 2014
Homologous recombination (HR)-mediated repair of DNA double-strand break (DSB)s is restricted to the post-replicative phases of the cell cycle. Initiation of HR in the G1 phase blocks non-homologous end joining (NHEJ) impairing DSB repair.
Young Eun Choi, Yunfeng Pan, Eunmi Park, Panagiotis Konstantinopoulos, Subhajyoti De, Alan D'Andrea, Dipanjan Chowdhury   +6 more
doaj   +1 more source

DNA methylation heterogeneity induced by collaborations between enhancers [PDF]

Journal of Computational Biology, 2020, 2020
During mammalian embryo development, reprogramming of DNA methylation plays important roles in the erasure of parental epigenetic memory and the establishment of na\"{i}ve pluripogent cells. Multiple enzymes that regulate the processes of methylation and demethylation work together to shape the pattern of genome-scale DNA methylation and guid the ...
arxiv   +1 more source

Optimization of high molecular weight DNA extraction methods in shrimp for a long-read sequencing platform [PDF]

PeerJ, 2020
Marine organisms are important to global food security as they are the largest source of animal proteins feeding mankind. Genomics-assisted aquaculture can increase yield while preserving the environment to ensure sufficient and sustainable production ...
Pacharaporn Angthong, Tanaporn Uengwetwanit, Wirulda Pootakham, Kanchana Sittikankaew, Chutima Sonthirod, Duangjai Sangsrakru, Thippawan Yoocha, Intawat Nookaew, Thidathip Wongsurawat, Piroon Jenjaroenpun, Wanilada Rungrassamee, Nitsara Karoonuthaisiri   +11 more
doaj   +2 more sources

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

Nature Communications, 2017
Glutaminase inhibition (GLSi) has promising activity against certain cancers. Here, the authors show that GLSi has no effect on multiple mouse models of pancreatic cancer and characterize the metabolic pathways activated in response to GLSi whose ...
Douglas E. Biancur, Joao A. Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M. Sousa, Xiaoxu Wang, Albert S. W. Sohn, Gerald C. Chu, Steven P. Gygi, J. Wade Harper, Wojciech Fendler, Joseph D. Mancias, Alec C. Kimmelman   +12 more
doaj   +1 more source