Results 31 to 40 of about 4,220,889 (382)
HyenaDNA: Long-Range Genomic Sequence Modeling at Single Nucleotide Resolution [PDF]
Neural Information Processing Systems, 2023 Genomic (DNA) sequences encode an enormous amount of information for gene regulation and protein synthesis. Similar to natural language models, researchers have proposed foundation models in genomics to learn generalizable features from unlabeled genome ...
Eric D Nguyen +12 more
semanticscholar +1 more source
DNA repair: Caretakers of the genome? [PDF]
Current Biology, 1997 Recent results show that the 8-oxoguanine DNA repair system is functionally conserved in bacteria and mammals. The bacterial system protects the genome from the mutagenic effects of oxidative stress; the role of the mammalian system is expected to be similar and defects in it may increase susceptibility to cancer.
openaire +3 more sources
TET2 inhibits differentiation of embryonic stem cells but does not overcome methylation-induced gene silencing [PDF]
, 2014 TET2 is a methylcytosine dioxygenase that is frequently mutated in myeloid malignancies, notably myelodysplasia and acute myeloid leukemia. TET2 catalyses the conversion of 5′-methylcytosine to 5′-hydroxymethylcytosine within DNA and has been implicated ...
Chevassut, Timothy +2 more
core +3 more sources
Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).
BioTechniques, 2000 Preparation of mouse genomic DNA for PCR is costly and laborious, primarily because of the difficulty in physically separating DNA from other tissue components. This level of purification is unnecessary for many PCR applications.
G. Truett +5 more
semanticscholar +1 more source
Definitions, 2020 Human blood DAT promoter methylation NucleoMag Blood 200 μL Transl Psychiatry 2015; 5:e648 Wiers et al. Effects of depressive symptoms and peripheral DAT methylation on neural reactivity to alcohol cues in alcoholism Automated isolation of genomic DNA ...
semanticscholar +1 more source
Harnessing sponge gourd: an alternative source of oil and protein for nutritional security
Frontiers in Nutrition, 2023 Luffa cylindrica (L.) Roem. is an important cucurbit crop that assures food security and dietary diversity among the poor communities. In the present study, seeds of 42 genotypes of Luffa cylindrica were evaluated for their potential use as oil seed crop.
Ruchi Tyagi +7 more
doaj +1 more source
SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells
Genome Research, 2018 Simultaneous sequencing of the genome and transcriptome at the single-cell level is a powerful tool for characterizing genomic and transcriptomic variation and revealing correlative relationships.
K. Han +17 more
semanticscholar +1 more source
DNMTs are required for delayed genome instability caused by radiation [PDF]
, 2012 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited ...
Anderson, RM +10 more
core +2 more sources
The complete mitochondrial genome of Cepola schlegelii from the East China Sea
Mitochondrial DNA. Part B. Resources, 2022 Cepola schlegelii (Bleeker 1854) belongs to the genus Cepola in the family Cepolidae and order Priacanthiformes. The complete mitochondrial genome of C. schlegelii was sequenced and analyzed by a high-throughput sequencing approach.
Panjiao Liang +5 more
doaj +1 more source
Comparison of three genomic DNA extraction methods to obtain high DNA quality from maize
Plant Methods, 2017 The world’s top three cereals, based on their monetary value, are rice, wheat, and corn. In cereal crops, DNA extraction is difficult owing to rigid non-cellulose components in the cell wall of leaves and high starch and protein content in grains.
A. Abdel-latif, G. Osman
semanticscholar +1 more source