Results 41 to 50 of about 4,220,889 (382)

Therapeutic effects of a combined antibiotic-enzyme treatment on subclinical mastitis in lactating dairy cows

open access: yesVeterinární Medicína, 2016
: The objective of this study was to evaluate a combined antibiotic-enzyme therapy for Staphylococcus aureus mastitis and biofilm formation. A total of 141 cases of S.
B. Khoramian   +6 more
doaj   +1 more source

Ribose-Map: a bioinformatics toolkit to map ribonucleotides embedded in genomic DNA

open access: yesNucleic Acids Research, 2018
Recent advances in high-throughput sequencing techniques have made it possible to tag ribonucleoside monophosphates (rNMPs) embedded in genomic DNA for sequencing.
Alli L. Gombolay   +2 more
semanticscholar   +1 more source

Mitochondrial DNA: A disposable genome?

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2015
In mammalian cells, mitochondria are the only organelles besides the nucleus that house genomic DNA. The mammalian mitochondrial genome is represented by prokaryotic-type, circular, highly compacted DNA molecules. Today, more than a half-century after their discovery, the biology of these small and redundant molecules remains much less understood than ...
Shokolenko, Inna N.   +1 more
openaire   +2 more sources

CAS9 is a genome mutator by directly disrupting DNA-PK dependent DNA repair pathway. [PDF]

open access: yes, 2020
With its high efficiency for site-specific genome editing and easy manipulation, the clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR associated protein 9 (CAS9) system has become the most widely used gene editing technology in ...
Chen, Qu   +6 more
core  

Human THO–Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability [PDF]

open access: yes, 2017
R-loops, formed by co-transcriptional DNA–RNA hybrids and a displaced DNA single strand (ssDNA), fulfill certain positive regulatory roles but are also a source of genomic instability.
Aguilera López, Andrés   +5 more
core   +1 more source

Spore PCR and qPCR Methods for Rapid Detection of Five Colletotrichum Species Responsible for Pepper Anthracnose in Korea [PDF]

open access: yesResearch in Plant Disease
Pepper anthracnose, caused by Colletotrichum spp., leads to a decrease in the quantity of pepper fruit production. Molecular diagnosis is crucial for rapid identification of pathogens and determination of fungicide resistance.
Haejun Jeong   +5 more
doaj   +1 more source

Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia

open access: yesEpilepsia, 2019
Focal cortical dysplasia (FCD) is a major cause of drug‐resistant focal epilepsy in children, and the clinicopathological classification remains a challenging issue in daily practice.
K. Kobow   +20 more
semanticscholar   +1 more source

Wolbachia and DNA barcoding insects: patterns, potential and problems [PDF]

open access: yes, 2012
Wolbachia is a genus of bacterial endosymbionts that impacts the breeding systems of their hosts. Wolbachia can confuse the patterns of mitochondrial variation, including DNA barcodes, because it influences the pathways through which mitochondria are ...
BC Schmidt   +75 more
core   +6 more sources

An optimal genomic DNA extraction method for shoots of four Dendrocalamus species based on membership function analysis

open access: yesBioTechniques, 2023
High-quality genomic DNA extraction is fundamental for the study of gene cloning and expression in plants. Therefore, this study evaluated several methods for extracting genomic DNA from shoots of four Dendrocalamus species to determine the optimal ...
Yingchun Ma   +6 more
doaj   +1 more source

DNA methylation of cancer genome [PDF]

open access: yesBirth Defects Research Part C: Embryo Today: Reviews, 2009
AbstractDNA methylation plays an important role in regulating normal development and carcinogenesis. Current understanding of the biological roles of DNA methylation is limited to its role in the regulation of gene transcription, genomic imprinting, genomic stability, and X chromosome inactivation.
Wai-Yee Chan   +4 more
openaire   +3 more sources

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