Results 51 to 60 of about 4,164,752 (382)

Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia

Epilepsia, 2019
Focal cortical dysplasia (FCD) is a major cause of drug‐resistant focal epilepsy in children, and the clinicopathological classification remains a challenging issue in daily practice.
K. Kobow, M. Ziemann, Harikrishnan Kaipananickal, I. Khurana, A. Mühlebner, M. Feucht, J. Hainfellner, T. Czech, E. Aronica, T. Pieper, H. Holthausen, M. Kudernatsch, H. Hamer, B. Kasper, K. Rössler, V. Conti, R. Guerrini, R. Coras, I. Blümcke, A. El-Osta, Antony Kaspi   +20 more
semanticscholar   +1 more source

DNA methylation of cancer genome [PDF]

Birth Defects Research Part C: Embryo Today: Reviews, 2009
AbstractDNA methylation plays an important role in regulating normal development and carcinogenesis. Current understanding of the biological roles of DNA methylation is limited to its role in the regulation of gene transcription, genomic imprinting, genomic stability, and X chromosome inactivation.
Wai-Yee Chan, Wai-Yee Chan, Owen M. Rennert, Tin-Lap Lee, Hoi-Hung Cheung   +4 more
openaire   +3 more sources

Spore PCR and qPCR Methods for Rapid Detection of Five Colletotrichum Species Responsible for Pepper Anthracnose in Korea [PDF]

Research in Plant Disease
Pepper anthracnose, caused by Colletotrichum spp., leads to a decrease in the quantity of pepper fruit production. Molecular diagnosis is crucial for rapid identification of pathogens and determination of fungicide resistance.
Haejun Jeong, Jonghan Yoon, Hoyoung Park, Min Son, Sook-Young Park, Kwang-Hyung Kim   +5 more
doaj   +1 more source

PipMaker--a web server for aligning two genomic DNA sequences.

Genome Research, 2000
PipMaker (http://bio.cse.psu.edu) is a World-Wide Web site for comparing two long DNA sequences to identify conserved segments and for producing informative, high-resolution displays of the resulting alignments.
S. Schwartz, Zheng Zhang, K. Frazer, A. Smit, C. Riemer, J. Bouck, R. Gibbs, R. Hardison, W. Miller   +8 more
semanticscholar   +1 more source

Isolation and Molecular Identification of Bacterial Strains to Study Biofilm Formation and Heavy Metals Resistance in Saudi Arabia

Journal of Pure and Applied Microbiology, 2019
Heavy metals found in nature and the excessive accumulations of heavy metals have an impact on humans and animals. Different effects resulted from the toxicity of heavy metal, that damage the functioning of different organs: brain, lungs, kidney and ...
Rania M. Makki, Ola I. M. El-Hamshary, Zainah M. Almarhabi   +2 more
doaj   +1 more source

Estimation of Pool Construction and Technical Error

Agriculture, 2021
Pooling animals with extreme phenotypes can improve the accuracy of genetic evaluation or provide genetic evaluation for novel traits at relatively low cost by exploiting large amounts of low-cost phenotypic data from animals in the commercial sector ...
John Keele, Tara McDaneld, Ty Lawrence, Jenny Jennings, Larry Kuehn   +4 more
doaj   +1 more source

CAS9 is a genome mutator by directly disrupting DNA-PK dependent DNA repair pathway. [PDF]

, 2020
With its high efficiency for site-specific genome editing and easy manipulation, the clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR associated protein 9 (CAS9) system has become the most widely used gene editing technology in ...
Chen, Qu, Fu, Xuemei, Kim, Jinchul, Liu, Jingfeng, Tang, Qingshuang, Xu, Shuxiang, Xu, Yang   +6 more
core  

DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets.

Molecular biology and evolution, 2017
We present version 6 of the DNA Sequence Polymorphism (DnaSP) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments.
J. Rozas, Albert Ferrer-Mata, Juan C. Sánchez-DelBarrio, S. Guirao-Rico, P. Librado, S. Ramos-Onsins, A. Sánchez‐Gracia   +6 more
semanticscholar   +1 more source

The DNA Components of the Chicken Genome [PDF]

European Journal of Biochemistry, 1979
The organization of the chicken genome was investigated by centrifuging chicken DNA (Mr= 57 × 106) in preparative Cs2SO4/Ag+ and Cs2SO4/BAMD density gradients [BAMD = 3,6‐bis(acetato‐mercurimethyl)dioxane]. An analysis by CsCl density gradient of the DNA fractions obtained from the preparative experiments revealed that 88% of the genome is made up of ...
Jordi Cortadas, Giorgio Bernardi, Michele Meunier-Rotival, Birgitta Olofsson, Gabriel Macaya   +4 more
openaire   +3 more sources

N 6-Hydroxymethyladenine: a hydroxylation derivative of N6-methyladenine in genomic DNA of mammals

Nucleic Acids Research, 2018
In addition to DNA cytosine methylation (5-methyl-2′-deoxycytidine, m5dC), DNA adenine methylation (N6-methyl-2′-deoxyadenosine, m6dA) is another DNA modification that has been discovered in eukaryotes.
Jun Xiong, Tian-tian Ye, Cheng-Jie Ma, Qing-Yun Cheng, Bifeng Yuan, Yuqi Feng   +5 more
semanticscholar   +1 more source