Results 61 to 70 of about 4,220,889 (382)
Detection of Epigenomic Network Community Oncomarkers [PDF]
In this paper we propose network methodology to infer prognostic cancer biomarkers based on the epigenetic pattern DNA methylation. Epigenetic processes such as DNA methylation reflect environmental risk factors, and are increasingly recognised for their
Bartlett, Thomas E., Zaikin, Alexey
core +2 more sources
Discovery of Double-Stranded Genomic DNA in Circulating Exosomes.
It is becoming increasingly clear that small vesicles released from cells (extracellular vesicles [EVs]) represent a heterogeneous population implicated in cell-to-cell communication. The classifications and nomenclature of EVs are evolving as enrichment
R. Kalluri, Valerie S. LeBleu
semanticscholar +1 more source
The Genomic Context and Corecruitment of SP1 Affect ERRα Coactivation by PGC-1α in Muscle Cells [PDF]
The peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) coordinates the transcriptional network response to promote an improved endurance capacity in skeletal muscle, eg, by coactivating the estrogen-related receptor-α (ERRα) in the ...
Baresic, Mario +4 more
core +1 more source
Gut microbiome as a biomarker of cardiometabolic disorders
Introduction and objective Cardiovascular diseases are the leading cause of death in Europe and worldwide. One of the most important risk factors for atherosclerosis are lipid metabolism disorders, in particular hipercholesterolaemia.
Anna Gózd-Barszczewska +4 more
doaj +1 more source
Genomics: DNA and diasporas [PDF]
Fatimah L. C. Jackson weighs up a study on the cultural politics of genetic testing among African Americans.
openaire +2 more sources
De novo Development and Characterization of Tetranucleotide Microsatellite Loci Markers from a Southeastern Population of the House Finch (Haemorhous mexicanus) [PDF]
Microsatellites are short tandem repeats (e.g. TAGATAGA) of base pairs in a species’ genome. High mutation rates in these regions produce variation in the number of repeats across individuals that can be utilized to study patterns of population- and ...
Barron, Douglas G +2 more
core +3 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Heavy metals found in nature and the excessive accumulations of heavy metals have an impact on humans and animals. Different effects resulted from the toxicity of heavy metal, that damage the functioning of different organs: brain, lungs, kidney and ...
Rania M. Makki +2 more
doaj +1 more source
Ab initio gene finding in Drosophila genomic DNA.
Ab initio gene identification in the genomic sequence of Drosophila melanogaster was obtained using (human gene predictor) and Fgenesh programs that have organism-specific parameters for human, Drosophila, plants, yeast, and nematode.
A. Salamov, V. Solovyev
semanticscholar +1 more source

