Results 81 to 90 of about 4,164,752 (382)
DNA methylation profiling of genomic DNA isolated from urine in diabetic chronic kidney disease: A pilot study. [PDF]
PLoS ONE, 2018 To characterise the genomic DNA (gDNA) yield from urine and quality of derived methylation data generated from the widely used Illuminia Infinium MethylationEPIC (HM850K) platform and compare this with buffy coat samples.DNA methylation is the most ...
Ashani Lecamwasam +5 more
doaj +1 more source
Inflammation, DNA-centered radicals, and oxidative genotoxicity: The role of HOCl produced by myeloperoxidase in carcinogenesis [PDF]
, 2009 Myeloid cells (macrophages and neutrophils) infiltrate and synthesize myeloperoxidase (MPO) in sites of inflammation, producing gentotoxicity. In RAW 264.7 macrophages, bacterial lipopolysaccharide (LPS) induces superoxide radical anion, nuclear ...
Dario C. Ramirez +2 more
core +2 more sources
Ab initio gene finding in Drosophila genomic DNA.
Genome Research, 2000 Ab initio gene identification in the genomic sequence of Drosophila melanogaster was obtained using (human gene predictor) and Fgenesh programs that have organism-specific parameters for human, Drosophila, plants, yeast, and nematode.
A. Salamov, V. Solovyev
semanticscholar +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Progress in Fishery SciencesRuditapes philippinarum—a marine bivalve mollusc known for its adaptability across a range of temperatures, salinities, and habitats—thrives primarily in tidal flats and shallow marine areas. It is an ideal candidate for high-density cultivation in tidal
Lei ZHANG +7 more
doaj +1 more source
Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women. [PDF]
PLoS ONE, 2013 Abnormal one-carbon metabolism may lead to general genomic (global) hypomethylation, which may predispose an individual to the development of colorectal neoplasia.We evaluated the association between pre-diagnostic leukocyte genomic DNA methylation level
Hongmei Nan +7 more
doaj +1 more source
Genomic homogeneity in fibrolamellar carcinomas [PDF]
, 2001 Background-Fibrolamellar carcinoma (FLC) is a variant of hepatocellular carcinoma (HCC) with distinctive clinical and histological features. To date there have been few studies on the genotypic aspects of FLC and no previous attempts have been made to ...
Davidson, BR +4 more
core +1 more source
Plant Methods, 2014 Next-generation sequencing technologies rely on high quality DNA that is suitable for library preparation followed by sequencing. Some plant species store large amounts of phenolics and polysaccharides within their leaf tissue making genomic DNA ...
A. Healey +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Gut microbiome as a biomarker of cardiometabolic disorders
Annals of Agricultural and Environmental Medicine, 2017 Introduction and objective Cardiovascular diseases are the leading cause of death in Europe and worldwide. One of the most important risk factors for atherosclerosis are lipid metabolism disorders, in particular hipercholesterolaemia.
Anna Gózd-Barszczewska +4 more
doaj +1 more source