Results 131 to 140 of about 131,595 (265)

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

Exploration, EarlyView.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu, Xue Xia, Yingfang Chen, Haoying Yang, Xiaochen Chen, Lei Cai, Bingyang Shi   +6 more
wiley   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

Future Postharvest and Food, EarlyView.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq, Sajad Ahmad Mir, Zahida Naseem   +2 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Prognostic Impact of Tumor Stage and Growth Pattern in Sinonasal Adenoid Cystic Carcinoma: A 15‐Year Population‐Based Study

Head &Neck, EarlyView.
ABSTRACT Background Sinonasal adenoid cystic carcinoma (AdCC) has a limited prognosis. This study assesses its incidence and prognostic factors in The Netherlands, focusing on histopathological features. Methods Adult patients diagnosed during 2008–2022 were retrieved through the Netherlands Cancer Registry and the Dutch Pathology Registry.
Lise J. van de Velde, Gerben E. Breimer, Lot A. Devriese, Mischa de Ridder, W. F. Julius Scheurleer, Weibel W. Braunius, Remco de Bree, Boukje A. C. van Dijk, Liza A. Hoveling, Johannes A. Rijken   +9 more
wiley   +1 more source

WCN24-1870 CHRONIC RENAL LESIONS IN PATIENTS WITH RENAL CELL CARCINOMA ARE ASSOCIATED WITH ARISTOLOCHIC ACID EXPOSURE AND FASTER ACCUMULATION OF DNA DAMAGE

Kidney International Reports
Behnoush ABEDI-ARDEKANI, Fannie Martin, Sergey Senkin, Sarah Moody, Thomas Cattiaux, Yichen Wang, Aida Ferreiro-Iglesias, Valerie Gaborieau, Sandra Perdomo, Laura Humphreys, Michael R. Stratton, Paul Brennan, Matthieu Foll, Nicolas Alcala   +13 more
doaj   +1 more source

Estimating the contribution to transmission of asymptomatic tuberculosis from population-based genomic epidemiology studies. [PDF]

Emerg Microbes Infect
Li M, Cai L, Gao Q.
europepmc   +1 more source

Genomic Epidemiology of Resurgent Hepatitis A in Florida, 2018-2022. [PDF]

J Infect Dis
Doyle TJ, Buck BH, Locksmith TJ, McGruder-Rawson BM, Khudyakov Y, Blackmore C.   +5 more
europepmc   +1 more source

Transdisciplinary training to address challenges in genomic epidemiology of infectious diseases. [PDF]

Front Public Health
Hong SL, Stockman M, Nova Blanco JR, Van Cleemput C, Ahouidi A, Armién B, Bento A, Bollen N, Conde Pereira C, Freitas C, Hofstra M, Jordan MR, Kashima S, Gonçalves CCM, Campelo de Albuquerque E Melo CF, Nahata K, de Oliveira EC, Parra L, Saenz C, de Souza W, Stanojevic M, Rabinowitz PM, Vandamme AM.   +22 more
europepmc   +1 more source

Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification

International Journal of Cancer, EarlyView.
What's New? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez, Carla Debernardi, Alessandra Allione, Elton Jalis Herman, Simonetta Guarrera, Daniela Ferrante, Anna Aspesi, Marika Sculco, Marta La Vecchia, Carlotta Sacerdote, Federica Grosso, Christina M. Lill, Giovanna Masala, Marcela Guevara, Matthias B. Schulze, Salvatore Panico, Yaszan Asgari, Seehyun Park, Giovanna Tagliabue, Anne Tjønneland, Antonio Agudo, Elisabete Weiderpass, Corrado Magnani, Irma Dianzani, Paolo Vineis, Elisabetta Casalone, Giuseppe Matullo   +26 more
wiley   +1 more source