Results 161 to 170 of about 131,595 (265)

The rise and global spread of IMP carbapenemases (1996-2023): a genomic epidemiology study. [PDF]

Nat Commun
Vezina B, Morampalli BR, Nguyen HA, Gomez-Simmonds A, Peleg AY, Macesic N.   +5 more
europepmc   +1 more source

Bizard: A Community‐Driven Platform for Accelerating and Enhancing Biomedical Data Visualization

iMetaMed, EarlyView.
Bizard is an open‐source platform that consolidates customizable biomedical data visualization scripts, providing an intuitive interface, tutorials, and community support to enhance analysis and accelerate progress in precision medicine. https://openbiox.github.io/Bizard/ ABSTRACT Biomedical research increasingly relies on heterogeneous, high ...
Kexin Li, Hu Zheng, Kexin Huang, Yinying Chai, Yujie Peng, Chunyang Wang, Xuyang Yi, Zilun Jin, Hong Yang, Yun Peng, Ying Shi, Xinhe Lu, Jiarui Bian, Yirun Wang, Rongao Kou, Demin Gao, Hanbo Zhao, Juan Zhang, Dan Huang, Kaiyu Zhu, Chenxu Wu, Zeruo Yang, Zheng Kuang, Bin Yan, Mo Liu, Zhiwei Bao, Yuzhong Peng, Benben Miao, Jianming Zeng, Jianfeng Li, Peng Luo, Shixiang Wang   +31 more
wiley   +1 more source

Genomic epidemiology of healthcare-associated respiratory virus infections in Pittsburgh, Pennsylvania, 2018-2020. [PDF]

Infect Control Hosp Epidemiol
Rangachar Srinivasa V, Griffith MP, Sundermann AJ, Mills E, Raabe NJ, Waggle KD, Shutt KA, Phan T, Wang-Erickson AF, Snyder GM, Van Tyne D, Pless LL, Harrison LH.   +12 more
europepmc   +1 more source

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Evaluation of Oxford Nanopore Technologies workflows for genomic epidemiology of outbreak-associated bacterial isolates in the clinical setting. [PDF]

Microb Genom
Neuenschwander S, Borcard L, Gempeler S, Terrazos Miani MA, Casanova C, Ramette A.   +5 more
europepmc   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

iMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang, Shuzi Liu, Laurence Don Wai Luu, Yongzhi Zhai, Chenliang Zhu, Zhaomin Feng, Yao Tan, Linglong Wan, Jie Wang, Juan Zhou, Jing Wang, Lixin Xie, Quanyi Wang, Fei Xie   +13 more
wiley   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Genomic epidemiology of Colombian resistant <i>Candida auris</i> isolates. [PDF]

Antimicrob Agents Chemother
Alvarado Casas ML, Triana Díaz JA, Montilla-Escudero E, Prada Cardozo DA, Escandón Hernández P.   +4 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Genomic Epidemiology

, 2015
Lund, Ole, Thomsen, Martin, Bellod Cisneros, Jose Luis, Ahrenfeldt, Johanne, Tetzschner, Anna Maria Malberg, Leekitcharoenphon, Shinny, Kaas, Rolf Sommer, Lukjancenko, Oksana, Aarestrup, Frank   +8 more
openaire   +1 more source