Results 161 to 170 of about 305,884 (298)

WCN24-1870 CHRONIC RENAL LESIONS IN PATIENTS WITH RENAL CELL CARCINOMA ARE ASSOCIATED WITH ARISTOLOCHIC ACID EXPOSURE AND FASTER ACCUMULATION OF DNA DAMAGE

Kidney International Reports
Behnoush ABEDI-ARDEKANI, Fannie Martin, Sergey Senkin, Sarah Moody, Thomas Cattiaux, Yichen Wang, Aida Ferreiro-Iglesias, Valerie Gaborieau, Sandra Perdomo, Laura Humphreys, Michael R. Stratton, Paul Brennan, Matthieu Foll, Nicolas Alcala   +13 more
doaj   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Genomic Epidemiology of Resurgent Hepatitis A in Florida, 2018-2022. [PDF]

J Infect Dis
Doyle TJ, Buck BH, Locksmith TJ, McGruder-Rawson BM, Khudyakov Y, Blackmore C.   +5 more
europepmc   +1 more source

Understanding pre‐eclampsia and fetal growth restriction at high altitude: A narrative review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pre‐eclampsia (PE) and fetal growth restriction (FGR) are among the leading causes of maternal and perinatal morbidity and mortality worldwide. Both conditions are more frequent and severe at high altitudes due to physiological changes in oxygen availability and vascular adaptation.
Víctor S. Rangel, Juliana Malagón Castillo, Juan David Duarte, Mariana Abril Barreto, Alejandra Vivas Ramirez, José Alejandro Daza, Ángela María Ruiz‐Sternberg   +6 more
wiley   +1 more source

Transdisciplinary training to address challenges in genomic epidemiology of infectious diseases. [PDF]

Front Public Health
Hong SL, Stockman M, Nova Blanco JR, Van Cleemput C, Ahouidi A, Armién B, Bento A, Bollen N, Conde Pereira C, Freitas C, Hofstra M, Jordan MR, Kashima S, Gonçalves CCM, Campelo de Albuquerque E Melo CF, Nahata K, de Oliveira EC, Parra L, Saenz C, de Souza W, Stanojevic M, Rabinowitz PM, Vandamme AM.   +22 more
europepmc   +1 more source

Trends in Rheumatoid Arthritis Mortality Among Postmenopausal Women in the United States, 1999–2023

iMetaMed, EarlyView.
RA‐related mortality among U.S. postmenopausal women has markedly declined since 1999. Despite this overall progress, significant inequalities by race, region, and age highlight ongoing challenges in achieving equitable health outcomes. ABSTRACT Rheumatoid arthritis (RA) disproportionately affects postmenopausal women, who are at an increased risk of ...
Yuhui Zhao, Weilu Cui, Yayun Han, Jun Qiao, Minjing Chang   +4 more
wiley   +1 more source

Genomic epidemiology of SARS-CoV-2 in Peru from 2020 to 2024. [PDF]

Commun Med (Lond)
Sobkowiak B, Langdon A, Romero PE, Carrasco-Escobar G, Villa D, Cava Miller R, Cornejo Villanueva V, Dávila-Barclay A, Cuicapuza D, Salvatierra G, González L, Ayzanoa B, Huancachoque J, Marcos-Carbajal P, Gómez de la Torre JC, Barletta C, Chenet SM, Tapia-Limonchi R, Ballón J, Fernández P, Valderrama R, Leguía M, Delgado-Ratto C, Gotuzzo E, Zamudio C, Lescano W, Cárcamo C, Hurtado V, Lope-Pari P, Padilla-Rojas C, Jiménez-Vásquez V, Escalante-Maldonado O, Araujo-Castillo RV, Cabezas C, Colijn C, Tsukayama P.   +35 more
europepmc   +1 more source

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

Genomic epidemiology of Mycobacterium tuberculosis in Wales. [PDF]

Sci Rep
Pacchiarini N, Simkin F, Postans M, Ahern G, Song J, Brown C, Smith J, Williams C, Backx M, Thomas D, Connor TR, Williams C.   +11 more
europepmc   +1 more source

Move beyond free radical theory of aging

iMetaOmics, EarlyView.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source