Results 161 to 170 of about 1,050,824 (300)
BMEMat, EarlyView.This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao +3 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi +6 more
wiley +1 more source
Genomic and epidemiology of Salmonella
, 2018 Découverte il y a plus d’un siècle, Salmonella n’a cessé d’intriguer les chercheurs. Sa capacité à résister à de nombreux antibiotiques est de plus en plus préoccupante. La surveillance de ce pathogène repose sur un typage rapide et discriminant de façon à identifier le plus précocement possible les sources alimentaires contaminées.
openaire +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul +5 more
wiley +1 more source
Genomic Epidemiology to Inform Infection Control and Clinical Decision-Making
Infectious diseases and antimicrobial resistance remain major global public health challenges. Genomic epidemiology, which combines whole-genome sequencing (WGS) with clinical and microbiological data, enables earlier detection of pathogen transmission ...
Menif, Basma
core
Clinical Pharmacology &Therapeutics, EarlyView.Most clinical trial failures reflect unmeasured biological heterogeneity. Biography — chronic stress, adversity, trauma, and social isolation—is a neglected source of that heterogeneity, operating through the same molecular pathways drugs engage.
Ralph I. Horwitz
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Low‐dose aspirin is no longer routinely recommended for the primary prevention of cardiovascular disease in older adults due to a lack of net benefit over bleeding risk. We hypothesized that genetic subgroups may experience differential harm or benefit from aspirin therapy.
Peter D. Fransquet +8 more
wiley +1 more source
Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network
Clinical Pharmacology &Therapeutics, EarlyView.Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang +16 more
wiley +1 more source
Human Genome Epidemiology [PDF]
The American Journal of Human Genetics, 2004 openaire +1 more source